LBF20406PG02: Difference between revisions

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|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=
|Metabolism=
|Biological Activity= 15-deoxy-Delta^1 ^2 ^. ^1 ^4 -Prostaglandin J2 induces lipogenesis and adipocyte differentiation in cultured cell line.[[Reference:Kliewer_SA:Lenhard_JM:Willson_TM:Patel_I:Morris_DC:Lehmann_JM:,Cell,1995,83,813|{{RelationTable/GetFirstAuthor|Reference:Kliewer_SA:Lenhard_JM:Willson_TM:Patel_I:Morris_DC:Lehmann_JM:,Cell,1995,83,813}}]] 15-deoxy-Delta^1 ^2 ^. ^1 ^4 -Prostaglandin J2 shows powerful proapoptotic effects by inhibiting I kappa B alpha degradation.[[Reference:Ward_C:Dransfield_I:Murray_J:Farrow_SN:Haslett_C:Rossi_AG:,J. Immunol.,2002,168,6232|{{RelationTable/GetFirstAuthor|Reference:Ward_C:Dransfield_I:Murray_J:Farrow_SN:Haslett_C:Rossi_AG:,J. Immunol.,2002,168,6232}}]]
|Biological Activity= 15-deoxy- Delta ^1 ^2 ^. ^1 ^4 -Prostaglandin J2 induces lipogenesis and adipocyte differentiation in cultured cell line.[[Reference:Kliewer_SA:Lenhard_JM:Willson_TM:Patel_I:Morris_DC:Lehmann_JM:,Cell,1995,83,813|{{RelationTable/GetFirstAuthor|Reference:Kliewer_SA:Lenhard_JM:Willson_TM:Patel_I:Morris_DC:Lehmann_JM:,Cell,1995,83,813}}]] 15-deoxy- Delta ^1 ^2 ^. ^1 ^4 -Prostaglandin J2 shows powerful proapoptotic effects by inhibiting I kappa B alpha degradation.[[Reference:Ward_C:Dransfield_I:Murray_J:Farrow_SN:Haslett_C:Rossi_AG:,J. Immunol.,2002,168,6232|{{RelationTable/GetFirstAuthor|Reference:Ward_C:Dransfield_I:Murray_J:Farrow_SN:Haslett_C:Rossi_AG:,J. Immunol.,2002,168,6232}}]]
}}
}}


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Revision as of 14:00, 19 February 2010

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Upper classes: LB LBF



15-deoxy-Δ12.14-Prostaglandin J2
LBF20406PG02.png
Structural Information
11-oxo-prosta-5Z,9,12E,14Z-tetraen-1-oic acid
  • 15-deoxy-Δ12.14-Prostaglandin J2
  • 11-oxo-prosta-5Z,9,12E,14Z-tetraen-1-oic acid
Formula C20H28O3
Exact Mass 316.203844762
Average Mass 316.43452
SMILES C(CC=CC=C(C(=O)1)[C@@H](CC=CCCCC(O)=O)C=C1)CCC
Physicochemical Information
15-deoxy- Delta ^1 ^2 ^. ^1 ^4 -Prostaglandin J2 induces lipogenesis and adipocyte differentiation in cultured cell line. Kliewer_SA et al. 15-deoxy- Delta ^1 ^2 ^. ^1 ^4 -Prostaglandin J2 shows powerful proapoptotic effects by inhibiting I kappa B alpha degradation. Ward_C et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406PG02 See above. Kliewer_SA et al. 1995
n.a. LBF20406PG02 See above. Ward_C et al. 2002