LBF20407HO06: Difference between revisions

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|LipidBank=DFA8140
|LipidBank=DFA8140
|LipidMaps=LMFA03060001
|LipidMaps=LMFA03060001
|SysName=15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
|SysName=15S-Hydroxy- (cis-5,cis-8,cis-11,trans-13) -eicosatetraenoic acid
|Common Name=&&15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid&&
|Common Name=&&15S-Hydroxy- (5Z,8Z,11Z,13E) -eicosatetraenoic acid&&15-HETE&&
|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 236nm <FONT FACE="Symbol">e</FONT>: 27,000
|UV Spectra= lambda max: 236nm epsilon : 27,000
|Source=15(S)-HETE is the metabolite of arachidonic acid from the 15-lipoxygenase pathway.
|Source=15(S)-HETE is the metabolite of arachidonic acid from the 15-lipoxygenase pathway.
|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=
|Metabolism=
|Symbol=15(S)-HETE
|Biological Activity=15(S)-HETE is a potent inflammatory mediator and agonist of tracheal mucus secretions [[Reference:Ramis_I:Rosello-Catafau_J:Bulbena_O:Picado_C:Gelpi_E:,J. Chromatogr.,1989,496,416|{{RelationTable/GetFirstAuthor|Reference:Ramis_I:Rosello-Catafau_J:Bulbena_O:Picado_C:Gelpi_E:,J. Chromatogr.,1989,496,416}}]]. 15(S)-HETE also evokes contractions in a variety of blood vessels, and these responses are sensitive to thromboxane A2 receptor antagonists [[Reference:Van_Diest_MJ:Verbeuren_TJ:Herman_AG:,J. Pharmacol. Exp. Ther.,1991,256,194|{{RelationTable/GetFirstAuthor|Reference:Van_Diest_MJ:Verbeuren_TJ:Herman_AG:,J. Pharmacol. Exp. Ther.,1991,256,194}}]].
}}
{{MassbankSpectra|
UT000109
UT000110
UT000111
UT000112
UT000113
UT000114
UT000115
UT000116
UT000117
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Latest revision as of 00:00, 17 January 2014

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Upper classes: LB LBF



15S-Hydroxy- (5Z,8Z,11Z,13E) -eicosatetraenoic acid
LBF20407HO06.png
Structural Information
15S-Hydroxy- (cis-5,cis-8,cis-11,trans-13) -eicosatetraenoic acid
  • 15S-Hydroxy- (5Z,8Z,11Z,13E) -eicosatetraenoic acid
  • 15-HETE
15(S)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC[C@@H](C=CC=CCC=CCC=CCCCC(O)=O)O)CC
Physicochemical Information
15(S)-HETE is the metabolite of arachidonic acid from the 15-lipoxygenase pathway.
15(S)-HETE is a potent inflammatory mediator and agonist of tracheal mucus secretions Ramis_I et al.. 15(S)-HETE also evokes contractions in a variety of blood vessels, and these responses are sensitive to thromboxane A2 receptor antagonists Van_Diest_MJ et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20407HO06 See above. Ramis_I et al. 1989
n.a. LBF20407HO06 See above. Van_Diest_MJ et al. 1991