LBF20408LX01: Difference between revisions

No edit summary
No edit summary
 
(18 intermediate revisions by 2 users not shown)
Line 1: Line 1:
{{Lipid/Header}}
{{Hierarchy|{{PAGENAME}}}}
{{Hierarchy|{{PAGENAME}}}}


Line 4: Line 6:
|LipidBank=DFA8154
|LipidBank=DFA8154
|LipidMaps=LMFA03040002
|LipidMaps=LMFA03040002
|SysName=5S,14R,15S-trihydroxy-6E,8Z,10E,12E-eicosatetraenoic acid
|SysName=(5S,14R,15S) -Trihydroxy- (trans-6,cis-8,trans-10,trans-12) - eicosatetraenoic acid
|Common Name=&&lipoxin B_4&&
|Common Name=&&Lipoxin B_4&&(5S,14R,15S) -Trihydroxy- (6E,8Z,10E,12E) - eicosatetraenoic acid
|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 302nm <FONT FACE="Symbol">e</FONT>: 50,000
|UV Spectra= lambda max: 302nm  epsilon : 50,000
|Source=LXB4 is a trihydroxy fatty acid containing a conjugated tetraene, isolated when arachidonic acid is incubated with A23187-stimulated mixtures of human platelets and granulocytes [[Reference:Edenius_C:Stenke_L:Lindgren_JA:,Eur. J. Biochem.,1991,199,401|{{RelationTable/GetFirstAuthor|Reference:Edenius_C:Stenke_L:Lindgren_JA:,Eur. J. Biochem.,1991,199,401}}]].
|Chemical Synthesis=
|Metabolism=
|Symbol=LXB4
|Biological Activity=It is associated with several biological functions including leukocyte activation, natural killer cell inhibition, and monocyte migration and adhesion [[Reference:Ramstedt_U:Serhan_CN:Nicolaou_KC:Webber_SE:Wigzell_H:Samuelsson_B:,J. Immunol.,1987,138,266|{{RelationTable/GetFirstAuthor|Reference:Ramstedt_U:Serhan_CN:Nicolaou_KC:Webber_SE:Wigzell_H:Samuelsson_B:,J. Immunol.,1987,138,266}}]][[Reference:Maddox_JF:Serhan_CN:,J. Exp. Med.,1996,183,137|{{RelationTable/GetFirstAuthor|Reference:Maddox_JF:Serhan_CN:,J. Exp. Med.,1996,183,137}}]].
}}
}}
{{Lipid/Footer}}

Latest revision as of 07:55, 21 October 2010

LipidBank Top
(トップ)
Fatty acid
(脂肪酸)
Glycerolipid
(グリセロ脂質)
Sphingolipid
(スフィンゴ脂質)
Journals
(雑誌一覧)
How to edit
(ページの書き方)


Upper classes: LB LBF



Lipoxin B4
LBF20408LX01.png
Structural Information
(5S,14R,15S) -Trihydroxy- (trans-6,cis-8,trans-10,trans-12) - eicosatetraenoic acid
  • Lipoxin B4
  • (5S,14R,15S) -Trihydroxy- (6E,8Z,10E,12E) - eicosatetraenoic acid
LXB4
Formula C20H32O5
Exact Mass 352.224974134
Average Mass 352.46508
SMILES C(CCC(O)C(O)C=CC=CC=CC=CC(CCCC(O)=O)O)CC
Physicochemical Information
LXB4 is a trihydroxy fatty acid containing a conjugated tetraene, isolated when arachidonic acid is incubated with A23187-stimulated mixtures of human platelets and granulocytes Edenius_C et al..
It is associated with several biological functions including leukocyte activation, natural killer cell inhibition, and monocyte migration and adhesion Ramstedt_U et al. Maddox_JF et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 302nm ε : 50,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20408LX01 See above. Edenius_C et al. 1991
n.a. LBF20408LX01 See above. Maddox_JF et al. 1996
n.a. LBF20408LX01 See above. Ramstedt_U et al. 1987