LBF20503HO06: Difference between revisions

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|LipidBank=DFA8124
|LipidBank=DFA8124
|LipidMaps=LMFA03070007
|LipidMaps=LMFA03070007
|SysName=12R-hydroxy-5Z,8Z,12E,14Z,17Z-Eicosapentaenoic acid
|SysName=12R-Hydroxy- (cis-5,cis-8,trans-10,cis-14,cis-17) -eicosapentaenoic acid
|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 237nm <FONT FACE="Symbol">e</FONT>: 23,000
|Common Name=&&12R-Hydroxy- (5Z,8Z,10E,14Z,17Z) -eicosapentaenoic acid&&
|UV Spectra= lambda max: 237nm  epsilon : 23,000
|Source=12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin S. purpuratus [[Reference:Hawkins_DJ:Brash_AR:,J. Biol. Chem.,1987,262,7629|{{RelationTable/GetFirstAuthor|Reference:Hawkins_DJ:Brash_AR:,J. Biol. Chem.,1987,262,7629}}]].
|Chemical Synthesis=
|Metabolism=
|Symbol=12(R)-HEPE
|Biological Activity=The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE [[Reference:Masferrer_JL:Dunn_MW:Schwartzman_ML:,Invest. Ophthalmol. Vis. Sci.,1990,31,535|{{RelationTable/GetFirstAuthor|Reference:Masferrer_JL:Dunn_MW:Schwartzman_ML:,Invest. Ophthalmol. Vis. Sci.,1990,31,535}}]][[Reference:Conners_MS:Schwartzman_ML:Quan_X:Heilman_E:Chauhan_K:Falck_JR:Godfrey_HP:,J. Invest. Dermatol.,1995,104,47|{{RelationTable/GetFirstAuthor|Reference:Conners_MS:Schwartzman_ML:Quan_X:Heilman_E:Chauhan_K:Falck_JR:Godfrey_HP:,J. Invest. Dermatol.,1995,104,47}}]].
}}
}}
{{Lipid/Footer}}

Latest revision as of 07:37, 21 October 2010

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Upper classes: LB LBF



12R-Hydroxy- (5Z,8Z,10E,14Z,17Z) -eicosapentaenoic acid
LBF20503HO06.png
Structural Information
12R-Hydroxy- (cis-5,cis-8,trans-10,cis-14,cis-17) -eicosapentaenoic acid
  • 12R-Hydroxy- (5Z,8Z,10E,14Z,17Z) -eicosapentaenoic acid
12(R)-HEPE
Formula C20H30O3
Exact Mass 318.21949482599996
Average Mass 318.4504
SMILES C(CC=CC=C(CCC=CCC=CCCCC(O)=O)O)=CCC
Physicochemical Information
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin S. purpuratus Hawkins_DJ et al..
The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE Masferrer_JL et al. Conners_MS et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 237nm ε : 23,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20503HO06 See above. Conners_MS et al. 1995
n.a. LBF20503HO06 See above. Hawkins_DJ et al. 1987
n.a. LBF20503HO06 See above. Masferrer_JL et al. 1990