LBF232nnPG03: Difference between revisions

No edit summary
No edit summary
Line 11: Line 11:
|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=
|Metabolism=
|Biological Activity=17-phenyl trinor PGF2alpha amide is expected to show the typical intraocular effects of latanoprost. In vivo study revlealed that 17-phenyl trinor PGF2alpha amide was converted the amides of various PGs to the free acids.[[Reference:Woodward_DF:Krauss_AH:Chen_J:Lai_RK:Spada_CS:Burk_RM:Andrews_SW:Shi_L:Liang_Y:Kedzie_KM_et_al:,Surv. Ophthalmol.,2001,45 Suppl 4,S337|{{RelationTable/GetFirstAuthor|Reference:Woodward_DF:Krauss_AH:Chen_J:Lai_RK:Spada_CS:Burk_RM:Andrews_SW:Shi_L:Liang_Y:Kedzie_KM_et_al:,Surv. Ophthalmol.,2001,45 Suppl 4,S337}}]]
|Biological Activity=17-phenyl trinor PGF2 alpha  amide is expected to show the typical intraocular effects of latanoprost. In vivo study revlealed that 17-phenyl trinor PGF2 alpha  amide was converted the amides of various PGs to the free acids.[[Reference:Woodward_DF:Krauss_AH:Chen_J:Lai_RK:Spada_CS:Burk_RM:Andrews_SW:Shi_L:Liang_Y:Kedzie_KM_et_al:,Surv. Ophthalmol.,2001,45 Suppl 4,S337|{{RelationTable/GetFirstAuthor|Reference:Woodward_DF:Krauss_AH:Chen_J:Lai_RK:Spada_CS:Burk_RM:Andrews_SW:Shi_L:Liang_Y:Kedzie_KM_et_al:,Surv. Ophthalmol.,2001,45 Suppl 4,S337}}]]
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Revision as of 14:00, 19 February 2010

LipidBank Top
(トップ)
Fatty acid
(脂肪酸)
Glycerolipid
(グリセロ脂質)
Sphingolipid
(スフィンゴ脂質)
Journals
(雑誌一覧)
How to edit
(ページの書き方)


Upper classes: LB LBF



17-phenyl trinor Prostaglandin F_2α amide
LBF232nnPG03.png
Structural Information
9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-5Z,13E-dien-1-amide
  • 17-phenyl trinor Prostaglandin F_2α amide
  • 9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-5Z,13E-dien-1-amide
Formula C23H33NO4
Exact Mass 387.24095854899997
Average Mass 387.51246
SMILES C(c(c2)cccc2)C[C@@H](C=C[C@H]([C@H]1CC=CCCCC(N)=O)[C@@H](C[C@H](O)1)O)O
Physicochemical Information
17-phenyl trinor PGF2 alpha amide is expected to show the typical intraocular effects of latanoprost. In vivo study revlealed that 17-phenyl trinor PGF2 alpha amide was converted the amides of various PGs to the free acids. Woodward_DF et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF232nnPG03 See above. Woodward_DF et al. 2001