Template:Map/Phospholipid degradation: Difference between revisions
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=Phospholipid degradation= | =Phospholipid degradation= | ||
リン脂質の分解 | リン脂質の分解 | ||
{{Map/Instruction}} | |||
{| | {|style="text-align:center;" | ||
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| | |{{Map/MetaboliteSink|PL biosynthesis|Map/Glycerophospholipid}}<br/>diacyl glycerol (DG) <br/>[[Image:LBDG.png]] | ||
|phospholipase C<ref>細菌由来のホスホリパーゼCは菌体外に毒素とともに排出され様々な基質特異性を持つ。動物細胞のものはホスファチジルイノシトールの代謝回転に関与。</ref><br/>{{Map/ReactionLeft|P-choline|H2O|3.1.4.3}} | |||
| | |{{Map/MetaboliteSource|phosphatidyl choline}} (PC)<br/>[[Image:LBGPC.png]] | ||
|phospholipase D<ref>ホスホリパーゼDは高等植物、動物に広く存在する。カルジオリピン特異的なものは細菌中に存在。</ref><br/>{{Map/ReactionRight|H2O|choline|3.1.4.4}} | |||
| | |{{Map/MetaboliteSink|PL biosynthesis|Map/Glycerophospholipid}}<br/>phosphatidate (PA)<br/>[[Image:LBGPA.png]] | ||
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| | {| style="margin:auto;text-align:center;" | ||
{| style="margin:auto;" | |- | ||
|Phospholipase A1<ref name="pla">ホスホリパーゼA1,A2は膜結合性だが、高等生物のA2は細胞質、細胞外に属するものも存在する。</ref> | |||
|{{Map/ReactionLeftDown|H2O|R1-COOH|3.1.1.32}} | |||
|{{Map/ReactionRightDown|H2O|R2-COOH|3.1.1.4}} | |||
|Phospholipase A2<ref name="pla"/> | |||
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| | |colspan="2"|2-acyl lyso-PC | ||
| | |colspan="2"|1-acyl lyso-PC | ||
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|style=" | {| style="margin:auto;" | ||
|{{Map/ReactionRightDown|H2O|R2-COOH|3.1.1.5}} | |||
|Lysophospholipase | |||
|{{Map/ReactionLeftDown|H2O|R1-COOH|3.1.1.5}} | |||
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|} | |} | ||
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|style="text-align:center;"|''sn''-glycerol 3p<br/> | |style="text-align:center;"|''sn''-glycerol 3p<br/> | ||
|} | |} | ||
<references/> | |||
=Sphingomyelin degradation= | =Sphingomyelin degradation= | ||
{| style="text-align:center;" | |||
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| sphingomyelin<br/>[[LBSM.png]] | |||
| {{Map/ReactionRight|H2O|p-choline|3.1.4.-}} | |||
| ceramide<br/>(''N''-acyl sphingosine)<br/>[[LBSC.png]] | |||
| {{Map/ReactionRight|H2O|RCOOH|3.5.1.23}} | |||
| sphingosine<br/>''trans''-4-sphingenine<br/>[[LBS.png]] | |||
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| {{Map/ReactionDown|ATP|ADP|}} | |||
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| palmital<br/> | |||
| {{Map/ReactionLeft|p-ethanolamine|H2O|}} | |||
| sphingenine 1-phosphate<br/>[[LBSP.png]] | |||
|} | |||
Latest revision as of 02:41, 1 August 2009
Phospholipid degradation
リン脂質の分解
| ... central metabolite |
| ... other maps |
| ¤PL biosynthesis diacyl glycerol (DG) 
|
phospholipase C[1] 3.1.4.3  P-choline H2O |
phosphatidyl choline (PC)
|
phospholipase D[2] 3.1.4.4  H2O choline |
¤PL biosynthesis phosphatidate (PA) 
| ||||||||||||||||||||||
| ||||||||||||||||||||||||||
| sn-glycerol 3-phosphocholine | 3.1.4.2 H2O choline |
sn-glycerol 3p | ||||||||||||||||||||||||
Sphingomyelin degradation
| sphingomyelin LBSM.png |
3.1.4.- H2O p-choline |
ceramide (N-acyl sphingosine) LBSC.png |
3.5.1.23 H2O RCOOH |
sphingosine trans-4-sphingenine LBS.png | |||||
| |||||||||
| palmital |
p-ethanolamine H2O |
sphingenine 1-phosphate LBSP.png |
