Taguchi:Summary

Lipidbase：メタボロミクス、特にリピドミクスにおける分析手法のデータベース

How to Use

このデータベースは、脂質の分析から同定までが記載されている論文を掲載している。脂 質の網羅的・包括的解析に有用な分析手法をそれぞれの脂質（たとえばアシルグリセロ ール、リン脂質、糖脂質など）に分けて、抽出、精製、液体クロマトグラフィー、マスス ペクトロメトリー、脂質同定するまでの過程を簡単明瞭に理解できるようにした。詳細な 知識を得たいユーザーのために論文からPubMedの抄録のページへリンクを貼り、アクセ スを可能にした。

Contents

• Paper Summary: 論文、分析した脂質、使用した機器名の一覧表 (このページ)
• Lipid Class: 脂質略号一覧 (脂質名をクリックすると記述されている論文リストへ)
• Analytical Methods: 分析略号一覧 (使用機器名をクリックすると記述されている論文リストへ)

Analysis Flow

1. 　サンプルより脂質抽出
2. 　目的脂質の精製
3. 　液体クロマトグラフィー
4. 　マススペクトロメトリー
5. 　脂質の同定
6. 　多変量解析（主成分分析）

Paper Summary

Total 16 original papers

paper ID	authors	title	lipids	MS	LC
Taguchi:OP101 (PMID 17449863)	Houjou T   Hayakawa J   Watanabe R   Tashima Y   Maeda Y   Kinoshita T   Taguchi R.	Changes in molecular species profiles of glycosylphosphatidylinositol anchor precursors in early stages of biosynthesis	GPI-anchor	Q-TOF II   Q-TOF mi	UM
Taguchi:OP104 (PMID 18206977)	Ogiso H   Suzuki T   Taguchi R.	Development of a reverse-phase liquid chromatography electrospray ionization mass spectrometry method for lipidomics, improving detection of phosphatidic acid and phosphatidylserine	PA   PS   LPA   LPS	LTQ-Orbi	LC10AD
Taguchi:OP110 (PMID 18703820)	Ikeda K   Shimizu T   Taguchi R.	Targeted analysis of ganglioside and sulfatide molecular species by LC/ESI-MS/MS with theoretically expanded multiple reaction monitoring	SGC   GM1   GM2   GM3   GD1   GD2   GD3   GT1   GT2   GT3   GQ1	QTRAP	UM
Taguchi:OP113 (PMID 18956880)	Ogiso H   Taguchi R.	Reversed-Phase LC/MS Method for Polyphosphoinositide Analyses: Changes in Molecular Species Levels during Epidermal Growth Factor Activation in A431 Cells	PIP1   PIP2   PIP3	LTQ-Orbi	LC10AD
Taguchi:OP114 (PMID 18964370)	Nakanishi H   Iida Y   Shimizu T   Taguchi R.	Analysis of oxidized phosphatidylcholines as markers for oxidative stress, using multiple reaction monitoring with theoretically expanded data sets with reversed-phase liquid chromatography/tandem mass spectrometry	OxPC	QTRAP	AU   UM
Taguchi:OP121 (PMID 19481987)	Ikeda K   Oike Y   Shimizu T   Taguchi R.	Global analysis of triacylglycerols including oxidized molecular species by reverse-phase high resolution LC/ESI-QTOF MS/MS	AG   OxAG	Q-TOF	AU
Taguchi:OP129 (PMID 19880374)	Nakanishi H   Iida Y   Shimizu T   Taguchi R.	Separation and quantification of sn-1 and sn-2 fatty acid positional isomers in phosphatidylcholine by RPLC-ESIMS/MS	PC   OxPC	QTRAP	AU
Taguchi:OP131 (PMID 20069690)	Ogiiso H   Nakamura K   Yatomi Y   Shimizu T   Taguchi R.	Liquid chromatography/mass spectrometry analysis revealing preferential occurrence of non-arachidonate-containing phosphatidylinositol bisphosphate species in nuclei and changes in their levels during cell cycle	PIP2	LTQ-Orbi	LC10AD
Taguchi:OP134 (PMID 20452604)	Taguchi R   Ishikawa M.	Precise and global identification of phospholipid molecular species by an Orbitrap mass spectrometer and automated search engine Lipid Search	PC   PE   PG   PS   PI   SM	LTQ-Orbi	LC10AD
Taguchi:OP76 (PMID 10972995)	Taguchi R   Hayakawa J   Takeuchi Y   Ishida M.	Two-dimensional analysis of phospholipids by capillary liquid chromatography/electrospray ionization mass spectrometry	PE   PC   SM   PI   LPC	Quatro	HP1100
Taguchi:OP87 (PMID 15384179)	Ishida M   Yamazaki T   Houjou T   Imagawa M   Harada A   Inoue K   Taguchi R.	High-resolution analysis by nano-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for the identification of molecular species of phospholipids and their oxidized metabolites	PE   PC   SM   OxPC	APEX   Quatro	HP1100
Taguchi:OP88 (PMID 15565732)	Houjou T   Yamatani K   Nakanishi H   Imagawa M   Shimizu T   Taguchi R.	Rapid and selective identification of molecular species in phosphatidylcholine and sphingomyelin by conditional neutral loss scanning and MS3	PC   SM	QTRAP   Q-TOF mi	UM   LC10AD
Taguchi:OP90 (PMID )	Ishida M   Imagawa M   Shimizu T   Taguchii R	Specific detection of lysophosphatidic acids in serum extracts by tandem mass spectrometry	LPA	QTRAP
Taguchi:OP91 (PMID 15700236)	Houjou T   Yamatani K   Imagawa M   Shimizu T   Taguchi R.	A shotgun tandem mass spectrometric analysis of phospholipids with normal-phase and/or reverse-phase liquid chromatography/electrospray ionization mass spectrometry	PE   PC   SM   PI   PS	Q-TOF   QTRAP	UM   LC10AD
Taguchi:OP93 (PMID 15990370)	Taguchi R   Houjou T   Nakanishi H   Yamazaki T   Ishida M   Imagawa M   Shimizu T.	Focused lipidomics by tandem mass spectrometry	PC   PE   PS   PI   PG	QTRAP	LC10AD
Taguchi:OP94 (PMID 16407401)	Tajima Y   Taguchi R   Murata C   Ashida H   Kinoshita T   Maeda Y.	PGAP2 Is Essential for Correct Processing and Stable Expression of GPI-anchored Proteins	GPI-anchor	LCQ	LC10AD