Latest revision as of 02:41, 1 August 2009

Phospholipid degradation

リン脂質の分解

... central metabolite
... other maps

¤PL biosynthesis
diacyl glycerol (DG)

phospholipase C^[1]
3.1.4.3

P-choline H2O

phosphatidyl choline (PC)

phospholipase D^[2]
3.1.4.4

H2O choline

¤PL biosynthesis
phosphatidate (PA)

Phospholipase A1^[3]

H2O
3.1.1.32
R1-COOH

H2O
3.1.1.4
R2-COOH

Phospholipase A2^[3]

2-acyl lyso-PC

1-acyl lyso-PC

H2O
3.1.1.5
R2-COOH

Lysophospholipase

H2O
3.1.1.5
R1-COOH

sn-glycerol 3-phosphocholine

3.1.4.2

H2O choline

sn-glycerol 3p

sphingomyelin
LBSM.png

3.1.4.-

H2O p-choline

ceramide
(N-acyl sphingosine)
LBSC.png

3.5.1.23

H2O RCOOH

sphingosine
trans-4-sphingenine
LBS.png

ATP

ADP

palmital

p-ethanolamine H2O

sphingenine 1-phosphate
LBSP.png

@@ Line 1: / Line 1: @@
 =Phospholipid degradation=
 リン脂質の分解
+{{Map/Instruction}}
 {|style="text-align:center;"
 |-
-|diacyl glycerol<br/>[[Image:LBDG.png]]
+|{{Map/MetaboliteSink|PL biosynthesis|Map/Glycerophospholipid}}<br/>diacyl glycerol (DG) <br/>[[Image:LBDG.png]]
 |phospholipase C<ref>細菌由来のホスホリパーゼCは菌体外に毒素とともに排出され様々な基質特異性を持つ。動物細胞のものはホスファチジルイノシトールの代謝回転に関与。</ref><br/>{{Map/ReactionLeft|P-choline|H2O|3.1.4.3}}
 |{{Map/MetaboliteSource|phosphatidyl choline}} (PC)<br/>[[Image:LBGPC.png]]
 |phospholipase D<ref>ホスホリパーゼDは高等植物、動物に広く存在する。カルジオリピン特異的なものは細菌中に存在。</ref><br/>{{Map/ReactionRight|H2O|choline|3.1.4.4}}
-|phosphatidate<br/>[[Image:LBGPA.png]]
+|{{Map/MetaboliteSink|PL biosynthesis|Map/Glycerophospholipid}}<br/>phosphatidate (PA)<br/>[[Image:LBGPA.png]]
 |-
 |