Category:LBS/Biosynthesis/CeramideSyn: Difference between revisions

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| [http://www.uniprot.org/uniprot/O15121 DEGS1](DES1)
| [http://www.uniprot.org/uniprot/O15121 DEGS1](DES1)
| 1q42.11
| 1q42.11
|
|rowspan="2"| The enzyme hydroxylates DES to form phytoceramide.<ref>Michel C, van Echten-Deckert G. (1997) "Conversion of dihydroceramide to ceramide occurs at the cytosolic face of the endoplasmic reticulum" FEBS Lett 416(2):153-155 </ref>
|-
|-
| [http://www.uniprot.org/uniprot/Q6QHC5 DEGS2](DES2)
| [http://www.uniprot.org/uniprot/Q6QHC5 DEGS2](DES2)
| 14q32.2
| 14q32.2
| The enzyme hydroxylates DES to form phytoceramide.
|}
|}

Revision as of 13:18, 18 December 2017

serine
+
palmitoyl (16:0)-CoA

 serine palmitoyl
  transferase 		3-ketodihydro-
  sphingosine
(3-KDS)

  3-KDS
  reductase 		dihydrosphingosine
(DHS, d18:0) 		Cer synthase

fatty acyl CoA 		dihydroceramide
(DHCer)

  DHCer
  desaturase 		ceramide
(Cer)
Cytosolic surface of the endoplasmic reticulum (ER)
  1. ↑ Michel C, van Echten-Deckert G. (1997) "Conversion of dihydroceramide to ceramide occurs at the cytosolic face of the endoplasmic reticulum" FEBS Lett 416(2):153-155

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