LBF20406HO11: Difference between revisions

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|SysName=5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
|SysName=5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
|Common Name=&&5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid&&
|Common Name=&&5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid&&
|UV Spectra=lambdamax: 236nm epsilon: 27,000
|UV Spectra= lambda max: 236nm epsilon : 27,000
|Source=5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
|Source=5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
|Chemical Synthesis=
|Chemical Synthesis=

Revision as of 14:00, 19 February 2010

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Upper classes: LB LBF



5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
LBF20406HO11.png
Structural Information
5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
  • 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
5(S)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC=CCC=CCC=CC=C[C@H](CCCC(O)=O)O)CCC
Physicochemical Information
5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
5(S)-HETE is metabolized to 5-OxoETE by a 5-hydroxyeicosanoid dehydrogenase present in intact human polymorphonuclear leukocytes Powell_WS et al..
5(S)-HETE is incorporated specifically into phosphatidylcholine and glycerol esters causing the inhibition of prostaglandin I_2 and E_2 synthesis in histamine or arachidonic acid stimulated human endothelial cells Richards_CF et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406HO11 See above. Powell_WS et al. 1992
n.a. LBF20406HO11 See above. Richards_CF et al. 1986