LBF20406HO11

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Upper classes: LB LBF



5S-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
LBF20406HO11.png
Structural Information
5S-Hydroxy- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
  • 5S-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
  • 5-HETE
5(S)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC=CCC=CCC=CC=C[C@H](CCCC(O)=O)O)CCC
Physicochemical Information
5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
5(S)-HETE is metabolized to 5-OxoETE by a 5-hydroxyeicosanoid dehydrogenase present in intact human polymorphonuclear leukocytes Powell_WS et al..
5(S)-HETE is incorporated specifically into phosphatidylcholine and glycerol esters causing the inhibition of prostaglandin I_2 and E_2 synthesis in histamine or arachidonic acid stimulated human endothelial cells Richards_CF et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406HO11 See above. Powell_WS et al. 1992
n.a. LBF20406HO11 See above. Richards_CF et al. 1986