LBF20406HO11

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	DFA8129
LipidMaps	LMFA03060002
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20406HO11

5S-Hydroxy- (6-trans,8-cis,11-cis,14-cis) -icosatetraenoic acid
Structural Information
Systematic Name	5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
Common Name	5S-Hydroxy- (6-trans,8-cis,11-cis,14-cis) -icosatetraenoic acid
Symbol	5(S)-HETE
Formula	C20H32O3
Exact Mass	320.23514489
Average Mass	320.46628
SMILES	C(CC=CCC=CCC=CC=C[C@H](CCCC(O)=O)O)CCC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility
Source	5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
Chemical Synthesis
Metabolism	5(S)-HETE is metabolized to 5-OxoETE by a 5-hydroxyeicosanoid dehydrogenase present in intact human polymorphonuclear leukocytes Powell_WS et al..
Biological Activity	5(S)-HETE is incorporated specifically into phosphatidylcholine and glycerol esters causing the inhibition of prostaglandin I_2 and E_2 synthesis in histamine or arachidonic acid stimulated human endothelial cells Richards_CF et al..
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra	λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20406HO11 See above. Powell_WS et al. 1992 n.a. LBF20406HO11 See above. Richards_CF et al. 1986