LBF20406HO11: Difference between revisions

No edit summary
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 6: Line 6:
|LipidBank=DFA8129
|LipidBank=DFA8129
|LipidMaps=LMFA03060002
|LipidMaps=LMFA03060002
|SysName=5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
|SysName=5S-Hydroxy- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
|Common Name=&&5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid&&
|Common Name=&&5S-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid&&5-HETE&&
|UV Spectra=lambdamax: 236nm epsilon: 27,000
|UV Spectra= lambda max: 236nm epsilon : 27,000
|Source=5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
|Source=5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
|Chemical Synthesis=
|Chemical Synthesis=
Line 14: Line 14:
|Symbol=5(S)-HETE
|Symbol=5(S)-HETE
|Biological Activity=5(S)-HETE is incorporated specifically into phosphatidylcholine and glycerol esters causing the inhibition of prostaglandin I_2  and E_2  synthesis in histamine or arachidonic acid stimulated human endothelial cells [[Reference:Richards_CF:Johnson_AR:Campbell_WB:,Biochim. Biophys. Acta,1986,875,569|{{RelationTable/GetFirstAuthor|Reference:Richards_CF:Johnson_AR:Campbell_WB:,Biochim. Biophys. Acta,1986,875,569}}]].
|Biological Activity=5(S)-HETE is incorporated specifically into phosphatidylcholine and glycerol esters causing the inhibition of prostaglandin I_2  and E_2  synthesis in histamine or arachidonic acid stimulated human endothelial cells [[Reference:Richards_CF:Johnson_AR:Campbell_WB:,Biochim. Biophys. Acta,1986,875,569|{{RelationTable/GetFirstAuthor|Reference:Richards_CF:Johnson_AR:Campbell_WB:,Biochim. Biophys. Acta,1986,875,569}}]].
}}
{{MassbankSpectra|
UT000172
UT000173
UT000174
UT000175
UT000176
UT000177
UT000178
UT000179
UT000180
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Latest revision as of 00:00, 17 January 2014

LipidBank Top
(トップ)
Fatty acid
(脂肪酸)
Glycerolipid
(グリセロ脂質)
Sphingolipid
(スフィンゴ脂質)
Journals
(雑誌一覧)
How to edit
(ページの書き方)


Upper classes: LB LBF



5S-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
LBF20406HO11.png
Structural Information
5S-Hydroxy- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
  • 5S-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
  • 5-HETE
5(S)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC=CCC=CCC=CC=C[C@H](CCCC(O)=O)O)CCC
Physicochemical Information
5(S)-HETE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on arachidonic acid.
5(S)-HETE is metabolized to 5-OxoETE by a 5-hydroxyeicosanoid dehydrogenase present in intact human polymorphonuclear leukocytes Powell_WS et al..
5(S)-HETE is incorporated specifically into phosphatidylcholine and glycerol esters causing the inhibition of prostaglandin I_2 and E_2 synthesis in histamine or arachidonic acid stimulated human endothelial cells Richards_CF et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406HO11 See above. Powell_WS et al. 1992
n.a. LBF20406HO11 See above. Richards_CF et al. 1986