LBF20406HO20: Difference between revisions
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|SysName=5 (S) -Hydroxy-6,8,11,14- (E,Z,Z,Z) -eicosatetraenoic acid | |SysName=5 (S) -Hydroxy-6,8,11,14- (E,Z,Z,Z) -eicosatetraenoic acid | ||
|Common Name=&&5 (S) -Hydroxy-6,8,11,14- (E,Z,Z,Z) -eicosatetraenoic acid&& | |Common Name=&&5 (S) -Hydroxy-6,8,11,14- (E,Z,Z,Z) -eicosatetraenoic acid&& | ||
| | |Optical=METHYL ESTER ; [<FONT FACE="Symbol">a</FONT>]X<sub>D</sub><sup>23</sup>=+14.0°(C=2.0, BENZENE) | ||
|Solubility=DIETHYL ETHER [[Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816|{{RelationTable/GetFirstAuthor|Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816}}]] | |Solubility=DIETHYL ETHER [[Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816|{{RelationTable/GetFirstAuthor|Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816}}]] | ||
|Mass Spectra=METHYL ESTER ETHER ; m/e 406(M<SUP><FONT SIZE=-1>+</FONT></SUP>), 391, 375, 316, 305, 255, 216, 215, 203, 190, 155, 150, 143, 136, 105, 80, 79 [[Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816|{{RelationTable/GetFirstAuthor|Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816}}]] | |Mass Spectra=METHYL ESTER ETHER ; m/e 406(M<SUP><FONT SIZE=-1>+</FONT></SUP>), 391, 375, 316, 305, 255, 216, 215, 203, 190, 155, 150, 143, 136, 105, 80, 79 [[Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816|{{RelationTable/GetFirstAuthor|Reference:Borgeat_P:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1976,251,7816}}]] | ||
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|Chemical Synthesis= {{Image200|LBF20406HO20FT0001.gif}} | |Chemical Synthesis= {{Image200|LBF20406HO20FT0001.gif}} | ||
|Metabolism=When arachidonic acid is oxygenated by 5-lipoxygenase, 5(S)-hydroperoxy-6,,8,11,14-(E,Z,Z,Z)-eicosatetraenoic acid is produced [[Reference:Ford-Hutchinson_AW:Gresser_M:Young_RN:,Annu. Rev. Biochem.,1994,63,383|{{RelationTable/GetFirstAuthor|Reference:Ford-Hutchinson_AW:Gresser_M:Young_RN:,Annu. Rev. Biochem.,1994,63,383}}]]. The latter compound is reduced to a corresponding 5(S)-hydroxy acid with whole cells or crude enzyme preparations. | |Metabolism=When arachidonic acid is oxygenated by 5-lipoxygenase, 5(S)-hydroperoxy-6,,8,11,14-(E,Z,Z,Z)-eicosatetraenoic acid is produced [[Reference:Ford-Hutchinson_AW:Gresser_M:Young_RN:,Annu. Rev. Biochem.,1994,63,383|{{RelationTable/GetFirstAuthor|Reference:Ford-Hutchinson_AW:Gresser_M:Young_RN:,Annu. Rev. Biochem.,1994,63,383}}]]. The latter compound is reduced to a corresponding 5(S)-hydroxy acid with whole cells or crude enzyme preparations. | ||
|Symbol=5(S)-HETE | |||
}} | }} | ||
{{Lipid/Footer}} | {{Lipid/Footer}} | ||
Revision as of 21:00, 6 January 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | XPR6101 |
| LipidMaps | - |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406HO20 |
| 5 (S) -Hydroxy-6,8,11,14- (E,Z,Z,Z) -eicosatetraenoic acid | |
|---|---|
| |
| Structural Information | |
| 5 (S) -Hydroxy-6,8,11,14- (E,Z,Z,Z) -eicosatetraenoic acid | |
| |
| 5(S)-HETE | |
| Formula | C20H32O3 |
| Exact Mass | 320.23514489 |
| Average Mass | 320.46628 |
| SMILES | C(CC=CCC=CCC=CC=C[C@@H](CCCC(O)=O)O)CCC |
| Physicochemical Information | |
| METHYL ESTER ; [a]XD23=+14.0°(C=2.0, BENZENE) | |
| DIETHYL ETHER BorgeatPet al. | |
 | |
| When arachidonic acid is oxygenated by 5-lipoxygenase, 5(S)-hydroperoxy-6,,8,11,14-(E,Z,Z,Z)-eicosatetraenoic acid is produced Ford-Hutchinson_AW et al.. The latter compound is reduced to a corresponding 5(S)-hydroxy acid with whole cells or crude enzyme preparations. | |
| Spectral Information | |
| Mass Spectra | METHYL ESTER ETHER ; m/e 406(M+), 391, 375, 316, 305, 255, 216, 215, 203, 190, 155, 150, 143, 136, 105, 80, 79 BorgeatPet al. |
| UV Spectra | METHYL ESTER ; l MeOHmax = 235nm (e 30,500) BorgeatPet al. |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | |||||||||||||||
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