LBF20406LT03

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	XPR3111
LipidMaps	LMFA03020024
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20406LT03

12-oxo-Leukotriene B4
Structural Information
Systematic Name	5S-hydroxy-12-keto- [ 6Z, 8E, 10E, 14Z ] -eicosatetraenoic acid
Common Name	12-oxo-Leukotriene B4 5S-hydroxy-12-keto- [ 6Z, 8E, 10E, 14Z ] -eicosatetraenoic acid
Symbol
Formula	C20H30O4
Exact Mass	334.21440944799997
Average Mass	334.4498
SMILES	C(CC=CCC(C=CC=CC=C[C@H](CCCC(O)=O)O)=O)CCC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility	Soluble in ethanol, methanol, ethyl acetate, acetonitril
Source	This metabolite is derived from LTB4 by LTB4 12-hydroxydehydrogenase. LTB4 12-hydroxydehydrogenase is expressed most abunduntly in liver and kidney.
Chemical Synthesis
Metabolism
Biological Activity
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra	UV maxima 316 nm, Absorbance at 320 nm is 41000/M
IR Spectra
NMR Spectra
Other Spectra
Chromatograms	12-oxo-LTB4 is eluted at 7.8 min on RP-HPLC system as follows: Solvent:acetonitril/water/acetic acid, 50:50:0.01 (v/v/v), 0.01 % (w/v) Na2EDTA, pH 5.6 with ammonia Flow: 1 ml/min, isocratic Column: Cosmosil 5C18-AR (4.6 x 150 mm, Nacalai tesque, Tokyo) YokomizoTet al.

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20406LT03 See above. Ensor_CM et al. 1998 n.a. LBF20406LT03 See above. Primiano_T et al. 1996 n.a. LBF20406LT03 See above. Yokomizo_T et al. 1993 n.a. LBF20406LT03 See above. Yokomizo_T et al. 1996