LBF20407HO02: Difference between revisions
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{{Lipid/Header}} | |||
{{Hierarchy|{{PAGENAME}}}} | {{Hierarchy|{{PAGENAME}}}} | ||
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|LipidBank=DFA8104 | |LipidBank=DFA8104 | ||
|LipidMaps=- | |LipidMaps=- | ||
|SysName=5S,15S- | |SysName=(5S,15S) -Dihydroxy- (trans-6,cis-8,cis-10,trans-13) -eicosatetraenoic acid | ||
|Common Name=&&5S,15S- | |Common Name=&&(5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid&& | ||
|UV Spectra= | |UV Spectra= lambda max: 243nm epsilon : 33,500 | ||
|Source=5(S),15(S)-DiHETE is synthesized by 15-lipoxygenase from 5(S)-HETE [[Reference:Green_FA:,Lipids,1990,25,618|{{RelationTable/GetFirstAuthor|Reference:Green_FA:,Lipids,1990,25,618}}]]. | |||
|Chemical Synthesis= | |||
|Metabolism= | |||
|Symbol=5(S),15(S)-DiHETE | |||
|Biological Activity=5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 [[Reference:OFlaherty_JT:Thomas_MJ:,Prostaglandins Leukot. Med.,1985,17,199|{{RelationTable/GetFirstAuthor|Reference:OFlaherty_JT:Thomas_MJ:,Prostaglandins Leukot. Med.,1985,17,199}}]]. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED_{50} of 0.3 μ M[[Reference:Morita_E:Schroder_JM:Christophers_E:,J. Immunol.,1990,144,1893|{{RelationTable/GetFirstAuthor|Reference:Morita_E:Schroder_JM:Christophers_E:,J. Immunol.,1990,144,1893}}]]. | |||
}} | }} | ||
{{Lipid/Footer}} | |||
Latest revision as of 07:34, 21 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | DFA8104 |
| LipidMaps | - |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20407HO02 |
| (5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid | |
|---|---|
| |
| Structural Information | |
| (5S,15S) -Dihydroxy- (trans-6,cis-8,cis-10,trans-13) -eicosatetraenoic acid | |
| |
| 5(S),15(S)-DiHETE | |
| Formula | C20H32O4 |
| Exact Mass | 336.23005951199997 |
| Average Mass | 336.46567999999996 |
| SMILES | C(CCC(C=CCC=CC=CC=CC(CCCC(O)=O)O)O)CC |
| Physicochemical Information | |
| 5(S),15(S)-DiHETE is synthesized by 15-lipoxygenase from 5(S)-HETE Green_FA . | |
| 5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 OFlaherty_JT et al.. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED_{50} of 0.3 μ M Morita_E et al.. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | λ max: 243nm ε : 33,500 |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | ||||||||||||||||||||
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