LBF20407HO02

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	DFA8104
LipidMaps	-
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20407HO02

(5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid
Structural Information
Systematic Name	(5S,15S) -Dihydroxy- (trans-6,cis-8,cis-10,trans-13) -eicosatetraenoic acid
Common Name	(5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid
Symbol	5(S),15(S)-DiHETE
Formula	C20H32O4
Exact Mass	336.23005951199997
Average Mass	336.46567999999996
SMILES	C(CCC(C=CCC=CC=CC=CC(CCCC(O)=O)O)O)CC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility
Source	5(S),15(S)-DiHETE is synthesized by 15-lipoxygenase from 5(S)-HETE Green_FA .
Chemical Synthesis
Metabolism
Biological Activity	5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 OFlaherty_JT et al.. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED_{50} of 0.3 μ M Morita_E et al..
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra	λ max: 243nm ε : 33,500
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20407HO02 See above. Green_FA 1990 n.a. LBF20407HO02 See above. Morita_E et al. 1990 n.a. LBF20407HO02 See above. OFlaherty_JT et al. 1985