LBF20406OX02

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Upper classes: LB LBF



12-Oxo- (5Z,8Z,10E,14Z) -eicosatetraenoic acid
LBF20406OX02.png
Structural Information
12-Oxo- (cis-5,cis-8,trans-10,cis-14) -eicosatetraenoic acid
  • 12-Oxo- (5Z,8Z,10E,14Z) -eicosatetraenoic acid
12-OxoETE/12-KETE
Formula C20H30O3
Exact Mass 318.21949482599996
Average Mass 318.4504
SMILES C(CC=CCC(C=CC=CCC=CCCCC(O)=O)=O)CCC
Physicochemical Information
12-OxoETE is synthesized by human platelets and Aplaysia nervous tissue after incubation with arachidonic acid Falgueyret_JP et al. Fruteau_de_Laclos_B et al.. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE Falgueyret_JP et al. Falgueyret_JP et al..
12-OxoETE induces a rapid, dose related increase of cytoplasmic free calcium via a leukotriene B4 receptor or a common activation sequence Naccache_PH et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 280nm ε : 30,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406OX02 See above. Falgueyret_JP et al. 1990
n.a. LBF20406OX02 See above. Falgueyret_JP et al. 1988
n.a. LBF20406OX02 See above. Fruteau_de_Laclos_B et al. 1987
n.a. LBF20406OX02 See above. Naccache_PH et al. 1991