Category:LBS: Difference between revisions
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{| border="1" cellpadding="5" cellspacing="0" style="text-align:right;" | {| border="1" cellpadding="5" cellspacing="0" style="text-align:right;" | ||
|+ Table 1. | |+ Table 1. Glycosphingolipids and Phosphosphingolipids | ||
|- | |- | ||
! style="background:# | ! style="background:#dedede; text-align:center;" colspan="3"| | ||
Glycosphingolipids (Abbr. BASE = Galβ1-4Glcβ1-Cer) | |||
|- valign="top" | |- valign="top" | ||
| <big>Gala (Ga)</big><br/> | | <big> Gala (Ga)</big><br/> Galα-4(6)'''Galβ1'''-Cer | ||
| <big> Globo (Gb)</big><br/> Galα'''1-4''' BASE | |||
Galα-4(6)'''Galβ1'''-Cer | {| class="wikitable collapsible collapsed" | ||
| <big>Globo (Gb)</big><br/> | |- | ||
< | | (Galα1-3)<sub>n</sub>Galα1-4 BASE | ||
Galα'''1- | |- | ||
| <big>Isoglobo (iG)</big><br/> | | '''Galb1-3GalNAcb1-3'''Galα1-4 BASE | ||
|- | |||
Galα'''1-3''' BASE | | '''GlcNacβ1-6GalNAcβ1-3'''Galα1-4 BASE | ||
|} | |||
| <big>Isoglobo (iG)</big><br/> Galα'''1-3''' BASE | |||
|- | |- | ||
| | | | ||
| <big>Ganglio (Gg)</big><br/> | | <big> Ganglio (Gg)</big><br/> GalNAcβ'''1-4''' BASE | ||
| <big>Isoganglio (iG)</big><br/> GalNAcβ'''1-3''' BASE | |||
GalNAcβ'''1-4''' BASE | |||
| <big>Isoganglio (iG)</big><br/> | |||
GalNAcβ'''1-3''' BASE | |||
|- | |- | ||
| | | | ||
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{| border="0" | {| border="0" | ||
|- | |- | ||
|GalNAcβ'''<sup>1</sup> | |GalNAcβ'''<sup>1</sup>\<sub>4</sub>'''<br/> | ||
GlcNAcβ'''<sub>1</sub> | GlcNAcβ'''<sub>1</sub>/<sup>3</sup>''' | ||
| BASE | | BASE | ||
|} | |} | ||
| <big>Lacto (Lc)</big><br/> | | <big>Lacto (Lc)</big><br/> Glcβ'''1-3''' BASE | ||
Glcβ'''1-3''' BASE | |||
|- | |- | ||
| | | | ||
| | | | ||
| <big>Neolacto (nL)</big><br/> | | <big>Neolacto (nL)</big><br/> Galβ1-4GlcNAcβ'''1-3''' BASE | ||
Galβ1-4GlcNAcβ'''1-3''' BASE | |||
|} | |} | ||
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Revision as of 08:26, 22 November 2009
Sphingolipid (スフィンゴ脂質)
Class Overview
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Common Abbreviations よく使う略称
Cer | Ceramides | セラミド |
Sph | Sphingosine | スフィンゴシン |
Design of Sphingolipid Identifiers ID番号の設計
25-DIGIT(5+9+9+2)
L | B | S | a | a | : | x1 | x1 | y1 | z1 | z1 | w1 | w1 | c1 | c1 | : | x2 | x2 | y2 | z2 | z2 | w2 | w2 | c2 | c2 |
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Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids (Abbr. BASE = Galβ1-4Glcβ1-Cer) | |||||
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Gala (Ga) Galα-4(6)Galβ1-Cer |
Globo (Gb) Galα1-4 BASE
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Isoglobo (iG) Galα1-3 BASE | |||
Ganglio (Gg) GalNAcβ1-4 BASE |
Isoganglio (iG) GalNAcβ1-3 BASE | ||||
Lactoganglio (LG)
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Lacto (Lc) Glcβ1-3 BASE | ||||
Neolacto (nL) Galβ1-4GlcNAcβ1-3 BASE |