LBF20107PG03: Difference between revisions
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|IR Spectra=d,l-PGF1<FONT FACE="Symbol">a</FONT> ; KBr : <FONT FACE="Symbol">n</FONT> 3330, 1716, 967 cm<SUP><FONT SIZE=-1>-</FONT></SUP><SUP><FONT SIZE=-1>1</FONT></SUP> [[Reference:Miyano_M:Dorn_CR:Mueller_RA:,J. Org. Chem.,1972,37,1810|{{RelationTable/GetFirstAuthor|Reference:Miyano_M:Dorn_CR:Mueller_RA:,J. Org. Chem.,1972,37,1810}}]] | |IR Spectra=d,l-PGF1<FONT FACE="Symbol">a</FONT> ; KBr : <FONT FACE="Symbol">n</FONT> 3330, 1716, 967 cm<SUP><FONT SIZE=-1>-</FONT></SUP><SUP><FONT SIZE=-1>1</FONT></SUP> [[Reference:Miyano_M:Dorn_CR:Mueller_RA:,J. Org. Chem.,1972,37,1810|{{RelationTable/GetFirstAuthor|Reference:Miyano_M:Dorn_CR:Mueller_RA:,J. Org. Chem.,1972,37,1810}}]] | ||
|NMR Spectra=<SUP><FONT SIZE=-1>1</FONT></SUP>H-NMR(ACETONE-d<SUB><FONT SIZE=-1>6</FONT></SUB>, TMS) : <FONT FACE="Symbol">d</FONT> 5.50(2H, 13-,14-CH), 3.75-4.3(m, 3H), 0.88(t, 3H) [[Reference:Ramwell_PW:Shaw_JE:Clarke_GB:Grostic_MF:Kaiser_DG:Pike_JE:,Progr. Chem. Fats Other Lipids,1971,9,231|{{RelationTable/GetFirstAuthor|Reference:Ramwell_PW:Shaw_JE:Clarke_GB:Grostic_MF:Kaiser_DG:Pike_JE:,Progr. Chem. Fats Other Lipids,1971,9,231}}]]<SUP><FONT SIZE=-1>1</FONT></SUP>H-NMR(CD<SUB><FONT SIZE=-1>3</FONT></SUB>OD, TMS, 300MHz):<FONT FACE="Symbol">d</FONT>4.10(1H, 9-CH), 3.81(1H, 11-CH), 2.36(1H, 10<FONT FACE="Symbol">b</FONT>-CH), 1.57(1H, 10<FONT FACE="Symbol">a</FONT>-CH)[[Reference:De_Clercq_P:Samson_M:Tavernier_D:Van_Haver_D:Vandewalle_M:,J. Org. Chem.,1977,42,3140|{{RelationTable/GetFirstAuthor|Reference:De_Clercq_P:Samson_M:Tavernier_D:Van_Haver_D:Vandewalle_M:,J. Org. Chem.,1977,42,3140}}]] | |NMR Spectra=<SUP><FONT SIZE=-1>1</FONT></SUP>H-NMR(ACETONE-d<SUB><FONT SIZE=-1>6</FONT></SUB>, TMS) : <FONT FACE="Symbol">d</FONT> 5.50(2H, 13-,14-CH), 3.75-4.3(m, 3H), 0.88(t, 3H) [[Reference:Ramwell_PW:Shaw_JE:Clarke_GB:Grostic_MF:Kaiser_DG:Pike_JE:,Progr. Chem. Fats Other Lipids,1971,9,231|{{RelationTable/GetFirstAuthor|Reference:Ramwell_PW:Shaw_JE:Clarke_GB:Grostic_MF:Kaiser_DG:Pike_JE:,Progr. Chem. Fats Other Lipids,1971,9,231}}]]<SUP><FONT SIZE=-1>1</FONT></SUP>H-NMR(CD<SUB><FONT SIZE=-1>3</FONT></SUB>OD, TMS, 300MHz):<FONT FACE="Symbol">d</FONT>4.10(1H, 9-CH), 3.81(1H, 11-CH), 2.36(1H, 10<FONT FACE="Symbol">b</FONT>-CH), 1.57(1H, 10<FONT FACE="Symbol">a</FONT>-CH)[[Reference:De_Clercq_P:Samson_M:Tavernier_D:Van_Haver_D:Vandewalle_M:,J. Org. Chem.,1977,42,3140|{{RelationTable/GetFirstAuthor|Reference:De_Clercq_P:Samson_M:Tavernier_D:Van_Haver_D:Vandewalle_M:,J. Org. Chem.,1977,42,3140}}]] | ||
|Source=Prostaglandin F1<FONT FACE="Symbol">a</FONT> is contained in human seminal plasma in an amount of 3.6 microgram/ml [[Reference:Bergstrom_S:,Science,1967,157,382|{{RelationTable/GetFirstAuthor|Reference:Bergstrom_S:,Science,1967,157,382}}]];>, and is detected in ovine seminal plasma and seminal vesicle, human amniotic fluid, umbilical cord, placental vessels and decidua, frog spinal cord and intestine, and rat adrenal [[Reference:Horton_EW:,Experientia,1965,21,113|{{RelationTable/GetFirstAuthor|Reference:Horton_EW:,Experientia,1965,21,113}}]];>. | |||
|Chemical Synthesis=[[Reference:Miyano_M:Dorn_CR:Mueller_RA:,J. Org. Chem.,1972,37,1810|{{RelationTable/GetFirstAuthor|Reference:Miyano_M:Dorn_CR:Mueller_RA:,J. Org. Chem.,1972,37,1810}}]];> {{Image200|XPR1500FT0001.gif}} | |||
|Metabolism= | |||
}} | }} | ||
{{Lipid/Footer}} | {{Lipid/Footer}} | ||
Revision as of 22:00, 24 November 2009
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | XPR1500 |
| LipidMaps | LMFA03010137 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20107PG03 |
| PROSTAGLANDIN F_1α | |
|---|---|
| |
| Structural Information | |
| 7- [ 3 (R) ,5 (S) -Dihydroxy-2 (R) - (3 (S) -hydroxy-1 (E) -octenyl) cyclopentan-1 (R) -yl ] -heptanoic acid / (8R,9S,11R,13E,15S) -9,11,15-Trihydroxyprost-13-enoic acid | |
| |
| Formula | C20H36O5 |
| Exact Mass | 356.256274262 |
| Average Mass | 356.49684 |
| SMILES | C(CC[C@@H](O)C=C[C@H]([C@H]1CCCCCCC(O)=O)[C@@H](C[C@@H]1O)O)CC |
| Physicochemical Information | |
| 102-103°C | |
| DIETHYL ETHER, ETHYL ACETATE, METHANOL , ETHANOL Pike_JEet al. | |
| Prostaglandin F1a is contained in human seminal plasma in an amount of 3.6 microgram/ml Bergstrom_S ;>, and is detected in ovine seminal plasma and seminal vesicle, human amniotic fluid, umbilical cord, placental vessels and decidua, frog spinal cord and intestine, and rat adrenal Horton_EW ;>. | |
|
Miyano_M et al.;> File:XPR1500FT0001.gif | |
| Spectral Information | |
| Mass Spectra | m/e 356(M+), 338, 320 Ramwell_PW et al. |
| UV Spectra | |
| IR Spectra | d,l-PGF1a ; KBr : n 3330, 1716, 967 cm-1 MiyanoMet al. |
| NMR Spectra | 1H-NMR(ACETONE-d6, TMS) : d 5.50(2H, 13-,14-CH), 3.75-4.3(m, 3H), 0.88(t, 3H) Ramwell_PW et al.1H-NMR(CD3OD, TMS, 300MHz):d4.10(1H, 9-CH), 3.81(1H, 11-CH), 2.36(1H, 10b-CH), 1.57(1H, 10a-CH) De_ClercqPet al. |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | ||||||||||||||||||||||||||||||||||||||||||||||||||
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