LBF20406OX01: Difference between revisions
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|Chemical Synthesis= | |Chemical Synthesis= | ||
|Metabolism= | |Metabolism= | ||
|Symbol=5-OxoETE/5-KETE | |||
|Biological Activity=It stimulates cytosolic calcium levels in neutrophils with an EC of 2 nM [[Reference:Powell_WS:Zhang_Y:Gravel_S:,Biochemistry,1994,33,3927|{{RelationTable/GetFirstAuthor|Reference:Powell_WS:Zhang_Y:Gravel_S:,Biochemistry,1994,33,3927}}]]. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils [[Reference:OFlaherty_JT:Kuroki_M:Nixon_AB:Wijkander_J:Yee_E:Lee_SL:Smitherman_PK:Wykle_RL:Daniel:LW:,J. Immunol.,1996,157,336|{{RelationTable/GetFirstAuthor|Reference:OFlaherty_JT:Kuroki_M:Nixon_AB:Wijkander_J:Yee_E:Lee_SL:Smitherman_PK:Wykle_RL:Daniel:LW:,J. Immunol.,1996,157,336}}]][[Reference:OFlaherty_JT:Kuroki_M:Nixon_AB:Wijkander_J:Yee_E:Lee_SL:Smitherman_PK:Wykle_RL:Daniel_LW:,J. Biol. Chem.,1996,271,17821|{{RelationTable/GetFirstAuthor|Reference:OFlaherty_JT:Kuroki_M:Nixon_AB:Wijkander_J:Yee_E:Lee_SL:Smitherman_PK:Wykle_RL:Daniel_LW:,J. Biol. Chem.,1996,271,17821}}]]. | |||
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{{Lipid/Footer}} | {{Lipid/Footer}} |
Revision as of 21:00, 6 January 2010
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
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LipidBank | DFA8156 |
LipidMaps | - |
CAS | |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20406OX01 |
5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid | |
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Structural Information | |
5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid | |
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5-OxoETE/5-KETE | |
Formula | C20H30O3 |
Exact Mass | 318.21949482599996 |
Average Mass | 318.4504 |
SMILES | C(CC=CCC=CCC=CC=CC(CCCC(O)=O)=O)CCC |
Physicochemical Information | |
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils Powell_WS et al.. | |
It stimulates cytosolic calcium levels in neutrophils with an EC of 2 nM Powell_WS et al.. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils OFlaherty_JT et al. OFlaherty_JT et al.. | |
Spectral Information | |
Mass Spectra | |
UV Spectra | lmax: 279nm e: 22,100 |
IR Spectra | |
NMR Spectra | |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | |||||||||||||||||||||||||
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