LBF20407HO04

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	DFA8105
LipidMaps	LMFA03060050
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20407HO04

(8S,15S) -Dihydroxy- (5Z,9E,11Z,13E) -eicosatetraenoic acid
Structural Information
Systematic Name	(8S,15S) -Dihydroxy- (5-cis,9-trans,11-cis,13-trans) -icosatetraenoic acid
Common Name	(8S,15S) -Dihydroxy- (5Z,9E,11Z,13E) -eicosatetraenoic acid 8S,15S-dihydroxy-5Z,9E,11Z,13E-eicosatetraenoic acid
Symbol	8(S),15(S)-DiHETE
Formula	C20H32O4
Exact Mass	336.23005951199997
Average Mass	336.46567999999996
SMILES	C(CCC(C=CC=CC=CC(CC=CCCCC(O)=O)O)O)CC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility
Source	8(S),15(S)-DiHETE is formed when15(S)-HETE is subjected to further oxidation by 15-lipoxygenase Morita_E et al..
Chemical Synthesis
Metabolism
Biological Activity	8(S),15(S)-diHETE causes chemotaxis of human eosinophils with an ED _{50} of 1.5 μ M but is not chemotactic for neutrophils Morita_E et al.. 8(S),15(S)-diHETE exhibits hypoalgesic activity by antagonizing the hyperalgesic activity of 8(R),15(S)-diHETE and LTB 4 when measuring nociceptive activity in the rat hindpaw model of pain Oliw_EH .
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra	λ max: 269 nm ε : 40,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20407HO04 See above. Morita_E et al. 1990