LBF20407LX01: Difference between revisions
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|Symbol=LXA4 | |Symbol=LXA4 | ||
|Biological Activity=LXA is equipotent to LTB in inducing superoxide generation in human neutrophils (0.1 mu M) [[Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335|{{RelationTable/GetFirstAuthor|Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335}}]]. LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis promotion, natural killer cell inhibition, and monocyte migration and adhesion [[Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335|{{RelationTable/GetFirstAuthor|Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335}}]][[Reference:Ramstedt_U:Serhan_CN:Nicolaou_KC:Webber_SE:Wigzell_H:Samuelsson_B:,J. Immunol.,1987,138,266|{{RelationTable/GetFirstAuthor|Reference:Ramstedt_U:Serhan_CN:Nicolaou_KC:Webber_SE:Wigzell_H:Samuelsson_B:,J. Immunol.,1987,138,266}}]][[Reference:Maddox_JF:Serhan_CN:,J. Exp. Med.,1996,183,137|{{RelationTable/GetFirstAuthor|Reference:Maddox_JF:Serhan_CN:,J. Exp. Med.,1996,183,137}}]]. | |Biological Activity=LXA is equipotent to LTB in inducing superoxide generation in human neutrophils (0.1 mu M) [[Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335|{{RelationTable/GetFirstAuthor|Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335}}]]. LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis promotion, natural killer cell inhibition, and monocyte migration and adhesion [[Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335|{{RelationTable/GetFirstAuthor|Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335}}]][[Reference:Ramstedt_U:Serhan_CN:Nicolaou_KC:Webber_SE:Wigzell_H:Samuelsson_B:,J. Immunol.,1987,138,266|{{RelationTable/GetFirstAuthor|Reference:Ramstedt_U:Serhan_CN:Nicolaou_KC:Webber_SE:Wigzell_H:Samuelsson_B:,J. Immunol.,1987,138,266}}]][[Reference:Maddox_JF:Serhan_CN:,J. Exp. Med.,1996,183,137|{{RelationTable/GetFirstAuthor|Reference:Maddox_JF:Serhan_CN:,J. Exp. Med.,1996,183,137}}]]. | ||
|CAS=89663-86-5 | |||
}} | }} | ||
{{Lipid/Footer}} | {{Lipid/Footer}} |
Revision as of 04:38, 17 January 2014
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
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LipidBank | DFA8153 |
LipidMaps | LMFA03040001 |
CAS | 89663-86-5 |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20407LX01 |
Lipoxin A4 | |
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Structural Information | |
(5S,6R,15S) -Trihydroxy- (trans-7,trans-9,cis-11,trans-13) - eicosatetraenoic acid | |
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LXA4 | |
Formula | C20H32O5 |
Exact Mass | 352.224974134 |
Average Mass | 352.46508 |
SMILES | C(CCC(C=CC=CC=CC=CC(O)C(O)CCCC(O)=O)O)CC |
Physicochemical Information | |
LXA4 is formed in vitro by a number of mechanisms from arachidonic acid, 15-HpETE, and leukotriene A4 (LTA4 ) Edenius_C et al. Serhan_CN et al.. | |
LXA is equipotent to LTB in inducing superoxide generation in human neutrophils (0.1 mu M) Serhan_CN et al.. LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis promotion, natural killer cell inhibition, and monocyte migration and adhesion Serhan_CN et al. Ramstedt_U et al. Maddox_JF et al.. | |
Spectral Information | |
Mass Spectra | |
UV Spectra | λ max: 302nm ε : 50,000 |
IR Spectra | |
NMR Spectra | |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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