LBF20407LX01: Difference between revisions

No edit summary
No edit summary
Line 4: Line 4:


{{Metabolite
{{Metabolite
|LipidBank=DFA815
|LipidBank=DFA8153
|LipidMaps=LMFA03040001
|LipidMaps=LMFA03040001
|CAS=89663-86-5
|CAS=89663-86-5
|SysName=(5S,6R,15S) -Trihydroxy- (trans-7,trans-9,cis-11,trans-13) - eicosatetraenoic acid
|SysName=(5S,6R,15S) -Trihydroxy- (trans-7,trans-9,cis-11,trans-13) - eicosatetraenoic acid
|Common Name=&&Lipoxin A_4&&(5S,6R,15S) -Trihydroxy- (7E,9E,11Z,13E) -eicosatetraenoic acid&&
|Common Name=&&Lipoxin A_4&&(5S,6R,15S) -Trihydroxy- (7E,9E,11Z,13E) -eicosatetraenoic acid&&
|UV Spectra= lambda max: 302nm  epsilon : 50,000
|UV Spectra=lambda max: 302nm  epsilon : 50,000
|Source=LXA4 is formed in vitro by a number of mechanisms from arachidonic acid, 15-HpETE, and leukotriene A4 (LTA4 ) [[Reference:Edenius_C:Stenke_L:Lindgren_JA:,Eur. J. Biochem.,1991,199,401|{{RelationTable/GetFirstAuthor|Reference:Edenius_C:Stenke_L:Lindgren_JA:,Eur. J. Biochem.,1991,199,401}}]][[Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335|{{RelationTable/GetFirstAuthor|Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335}}]].
|Source=LXA4 is formed in vitro by a number of mechanisms from arachidonic acid, 15-HpETE, and leukotriene A4 (LTA4 ) [[Reference:Edenius_C:Stenke_L:Lindgren_JA:,Eur. J. Biochem.,1991,199,401|{{RelationTable/GetFirstAuthor|Reference:Edenius_C:Stenke_L:Lindgren_JA:,Eur. J. Biochem.,1991,199,401}}]][[Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335|{{RelationTable/GetFirstAuthor|Reference:Serhan_CN:Hamberg_M:Samuelsson_B:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,5335}}]].
|Chemical Synthesis=
|Chemical Synthesis=

Revision as of 05:51, 17 January 2014

LipidBank Top
(トップ)
Fatty acid
(脂肪酸)
Glycerolipid
(グリセロ脂質)
Sphingolipid
(スフィンゴ脂質)
Journals
(雑誌一覧)
How to edit
(ページの書き方)


Upper classes: LB LBF



Lipoxin A4
LBF20407LX01.png
Structural Information
(5S,6R,15S) -Trihydroxy- (trans-7,trans-9,cis-11,trans-13) - eicosatetraenoic acid
  • Lipoxin A4
  • (5S,6R,15S) -Trihydroxy- (7E,9E,11Z,13E) -eicosatetraenoic acid
LXA4
Formula C20H32O5
Exact Mass 352.224974134
Average Mass 352.46508
SMILES C(CCC(C=CC=CC=CC=CC(O)C(O)CCCC(O)=O)O)CC
Physicochemical Information
LXA4 is formed in vitro by a number of mechanisms from arachidonic acid, 15-HpETE, and leukotriene A4 (LTA4 ) Edenius_C et al. Serhan_CN et al..
LXA is equipotent to LTB in inducing superoxide generation in human neutrophils (0.1 mu M) Serhan_CN et al.. LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis promotion, natural killer cell inhibition, and monocyte migration and adhesion Serhan_CN et al. Ramstedt_U et al. Maddox_JF et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 302nm ε : 50,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20407LX01 See above. Adams_J et al. 1985
n.a. LBF20407LX01 See above. Brady_HR et al. 1996
n.a. LBF20407LX01 See above. Edenius_C et al. 1991
n.a. LBF20407LX01 See above. Fiore_S et al. 1994
n.a. LBF20407LX01 See above. Maddox_JF et al. 1996
n.a. LBF20407LX01 See above. Ramstedt_U et al. 1987
n.a. LBF20407LX01 See above. Serhan_CN 1994
n.a. LBF20407LX01 See above. Serhan_CN et al. 1984
n.a. LBF20407LX01 See above. Serhan_CN et al. 1984
n.a. LBF20407LX01 See above. Serhan_CN et al. 1986