Template:Map/Ether phospholipid: Difference between revisions
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=Ether Phospholipid Biosynthesis= | =Ether Phospholipid Biosynthesis= | ||
エーテルリン脂質の生合成 | |||
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|style="text-align:center;"|1-acyl dihydroxy acetone p | |style="text-align:center;"|1-acyl dihydroxy acetone p | ||
|{{Map/ReactionLeftRight|NADH|NAD+|[http://metabolomics.jp/wiki/Enzyme:1.1.1.8 1.1.1.8]}} | |{{Map/ReactionLeftRight|NADH|NAD+|[http://metabolomics.jp/wiki/Enzyme:1.1.1.8 1.1.1.8]}} | ||
|style="text-align:center;"|1-acyl ''sn''-glycerol 3p | |style="text-align:center;"|1-acyl ''sn''-glycerol 3p<br/>[[Image:LBG1C3P.png]] | ||
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|{{Map/ | |{{Map/ReactionDown35inout|R1-OH|<small>→R-COOH</small>|}}1-alkyl dihydroxy acetone p<ref>アルキル型を含むエーテルリン脂質はペルオキシソームで合成。ペルオキシソームを欠乏するZellweger症候群では血小板活性化因子PAFが著しく減少。</ref>{{Map/ReactionDown35inout|NADPH|<small>→NADP+</small>|}} | ||
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|style="text-align:center;"|[[Image:Arrow00d.png]] | |style="text-align:center;"|[[Image:Arrow00d.png]] | ||
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|1-alkyl ''sn''-glycerol 3p | |style="text-align:center;"|1-alkyl ''sn''-glycerol 3p<br/>[[Image:LBG1K3P.png]] | ||
{{Map/ReactionDown|R2-CO-CoA|CoA|[http://metabolomics.jp/wiki/Enzyme:2.3.1.51 2.3.1.51]}} | {{Map/ReactionDown|R2-CO-CoA|CoA|[http://metabolomics.jp/wiki/Enzyme:2.3.1.51 2.3.1.51]}} | ||
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|1-acyl ''sn''-glycerol 3p | |style="text-align:center;"|1-acyl ''sn''-glycerol 3p<br/>or lyso-phosphatidate<br/> | ||
{{Map/ReactionDown|R2-CO-CoA|CoA|[http://metabolomics.jp/wiki/Enzyme:2.3.1.51 2.3.1.51]}} | {{Map/ReactionDown|R2-CO-CoA|CoA|[http://metabolomics.jp/wiki/Enzyme:2.3.1.51 2.3.1.51]}} | ||
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|1-alkyl 2-acyl ''sn''-glycerol 3p | |style="text-align:center;"|1-alkyl 2-acyl ''sn''-glycerol 3p<br/>[[Image:LBG1K2C3P.png]] | ||
{{Map/ReactionDown|H2O|Pi|[http://metabolomics.jp/wiki/Enzyme:3.1.3.4 3.1.3.4]}} | {{Map/ReactionDown|H2O|Pi|[http://metabolomics.jp/wiki/Enzyme:3.1.3.4 3.1.3.4]}} | ||
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|1 | |style="text-align:center;"|1,2-diacyl ''sn''-glycerol 3p<br/>or phosphatidate<br/>[[Image:LBGPA.png]] | ||
{{Map/ReactionDown|H2O|Pi|[http://metabolomics.jp/wiki/Enzyme:3.1.3.4 3.1.3.4]}} | {{Map/ReactionDown|H2O|Pi|[http://metabolomics.jp/wiki/Enzyme:3.1.3.4 3.1.3.4]}} | ||
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|1-alkyl 2-acyl ''sn''-glycerol<br/> | |style="text-align:center;"|1-alkyl 2-acyl ''sn''-glycerol<br/> | ||
{{Map/ReactionDown35|CDP-choline|}} | {{Map/ReactionDown35|CDP-choline|}} | ||
platelet-activating factor (PAF; 2=acetyl)<br/>or plasmalogen<ref>プラスマローゲン（不飽和エーテルリン脂質）は飽和エーテルリン脂質の脱水素で生成。</ref> | platelet-activating factor (PAF; 2=acetyl)<br/>or plasmalogen<ref>プラスマローゲン（不飽和エーテルリン脂質）は飽和エーテルリン脂質の脱水素で生成。</ref> | ||
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|1,2-diacyl ''sn''-glycerol<br/> | |style="text-align:center;"|1,2-diacyl and triacyl ''sn''-glycerol<br/> | ||
[[Template:Map/Glycerophospholipid| | → [[Template:Map/Glycerophospholipid|<font style="background-color:skyblue">GPL biosynthesis</font> | ||
]] | ]] | ||
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<references/> | |||
Latest revision as of 07:08, 3 July 2009
Ether Phospholipid Biosynthesis
エーテルリン脂質の生合成
dihydroxy acetone p
|
1.1.1.8 NADH NAD+ |
sn-glycerol 3p
| ||||||||||
| 1-acyl dihydroxy acetone p | 1.1.1.8 NADH NAD+ |
1-acyl sn-glycerol 3p
| ||||||||||
|
| |||||||||||
1-alkyl sn-glycerol 3p
|
1-acyl sn-glycerol 3p or lyso-phosphatidate
| |||||||||||
1-alkyl 2-acyl sn-glycerol 3p
|
1,2-diacyl sn-glycerol 3p or phosphatidate 
| |||||||||||
1-alkyl 2-acyl sn-glycerol
platelet-activating factor (PAF; 2=acetyl) |
1,2-diacyl and triacyl sn-glycerol |
