Category:LBS/Biosynthesis/GIPC: Difference between revisions
(Created page with "{| style="text-align:center" |- | palmitoyl (16:0)-CoA<br/>+<br/>serine | SPT<br/>File:Arrow00r.png<br/> |3-keto sphinganine |KSR<br/>File:Arrow00r.png<br/> |sphingani...") |
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| colspan="4" style="background: | | colspan="4" style="background:darkseagreen;border-radius: 40px"| Lumen of endoplasmic reticulum (ER) | ||
| {{Map/ReactionDown|16:0-CoA||CS I<ref>CS can utilize a range of FA-CoAs (C16-24) but not hydroxy-FA-CoAs. See Sperling P, Heinz E. (2003) Biochim Biophys Acta 1632:1–15.</ref>}} | | {{Map/ReactionDown|16:0-CoA||CS I<ref>CS can utilize a range of FA-CoAs (C16-24) but not hydroxy-FA-CoAs. See Sperling P, Heinz E. (2003) Biochim Biophys Acta 1632:1–15.</ref>}} | ||
| rowspan="4" style="background: | | rowspan="4" style="background:darkseagreen;border-radius: 40px"| Lumen of endoplasmic reticulum (ER) | ||
| {{Map/ReactionDown|VLCFA-CoA||CS II}} | | {{Map/ReactionDown|VLCFA-CoA||CS II}} | ||
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| {{Map/ReactionDown|||Δ8 DES<br/>Δ4 DES<br/>FA-αOHase<br/>(C-9 MT in fungi)}} | | {{Map/ReactionDown|||Δ8 DES<br/>Δ4 DES<br/>FA-αOHase<br/>(C-9 MT in fungi)}} | ||
| {{Map/ReactionDown|||Δ8 DES<br/>FA-αOHase}} | | {{Map/ReactionDown|||Δ8 DES<br/>FA-αOHase}} | ||
| '''Bold | | '''Bold font = ceramides''' | ||
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| '''d18:1Δ8E/Z-h16:0''' | | '''d18:1Δ8E/Z-h16:0''' | ||
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|colspan="2" rowspan="3" valign="top"| '''Glc-ceramide'''<br/>Glc-d18:2 4E,8E/Z-h16:0<br/>Glc-d18:1 8E/Z-h16:0<br/>Glc-t18:1-hVLCFA | |colspan="2" rowspan="3" valign="top"| '''Glc-ceramide'''<br/>Glc-d18:2 4E,8E/Z-h16:0<br/>Glc-d18:1 8E/Z-h16:0<br/>Glc-t18:1-hVLCFA | ||
| | |rowspan="3" style="background:darkturquoise;border-radius: 40px"| Golgi | ||
| '''t18:1Δ8E/Z-hVLCFA'''<br/>(in Golgi) | | '''t18:1Δ8E/Z-hVLCFA'''<br/>(in Golgi) | ||
|- | |- | ||
| {{Map/ReactionDown|PI|DAG|IPCS<ref>Activity of IPCS is high in Fabaceae. See Bromley PE, Li YO, Murphy SM, Sumner CM, Lynch DV (2003) Archiv Biochem Biophys 417:219–226</ref>}} | | {{Map/ReactionDown|PI|DAG|IPCS<ref>Activity of IPCS is high in Fabaceae. See Bromley PE, Li YO, Murphy SM, Sumner CM, Lynch DV (2003) Archiv Biochem Biophys 417:219–226</ref>}} | ||
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| '''GIPC''' (in Golgi) | | '''GIPC''' (in Golgi) | ||
|} | |} | ||
<references/> | <references/> | ||
Revision as of 02:00, 12 February 2016
| palmitoyl (16:0)-CoA + serine |
SPT |
3-keto sphinganine | KSR |
sphinganine d18:0 |
LCB C-4 OHase
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phytosphinganine t18:0 |
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| Lumen of endoplasmic reticulum (ER) |
|
Lumen of endoplasmic reticulum (ER) |
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d18:0-16:0 | t18:0-VLCFA | |||||||||||||||
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Bold font = ceramides | |||||||||||||||
| d18:1Δ8E/Z-h16:0 | t18:1Δ8E/Z-hVLCFA | ||||||||||||||||
 +UDP-Glc
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+UDP-Glc 
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transport
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| Glc-ceramide Glc-d18:2 4E,8E/Z-h16:0 Glc-d18:1 8E/Z-h16:0 Glc-t18:1-hVLCFA |
Golgi | t18:1Δ8E/Z-hVLCFA (in Golgi) | |||||||||||||||
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| GIPC (in Golgi) | |||||||||||||||||
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