Category:LBS: Difference between revisions
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Glycosphingolipids (Abbr. ROOT = Galβ1-4Glcβ1-Cer) | Glycosphingolipids (Abbr. ROOT = Galβ1-4Glcβ1-Cer) | ||
|- valign="top" | |- valign="top" | ||
| <big>''' Gala | | <big>''' Gala [Ga]''' (56)</big><br/> Galα-4(6)'''Galβ1'''-Cer | ||
| <big>''' Globo | | <big>''' Globo [Gb]''' (31)</big><br/> Galα'''1-4''' ''ROOT'' | ||
| <big>'''Isoglobo | | <big>'''Isoglobo [iB]''' (11)</big><br/> Galα'''1-3''' ''ROOT'' | ||
|- | |- | ||
| style="vertical-align:top;" |<!---Gala---> | | style="vertical-align:top;" |<!---Gala---> | ||
{| class="collapsible | {| class="collapsible" border="0" cellspacing="0" width="180" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| | | ...-Galα1-4(6) [A] | ||
|- | |||
| ...-Galβ1-4(6) [B] | |||
|} | |} | ||
| style="vertical-align:top;" |<!---Globo---> | | style="vertical-align:top;" |<!---Globo---> | ||
{| class="collapsible | {| class="collapsible" border="0" cellspacing="0" width="180" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| ...-[Galα1-3]<sub>n</sub> | | ...-[Galα1-3]<sub>n</sub> [A] | ||
|- | |- | ||
| ...-Galb1-3GalNAcβ1-3 | | ...-Galb1-3GalNAcβ1-3 [B] | ||
|- | |- | ||
| ...-GlcNAcβ1-6GalNAcβ1-3 | | ...-GlcNAcβ1-6GalNAcβ1-3 [B] | ||
|- | |- | ||
| ...-GalNAcβ1-3 | | ...-GalNAcβ1-3 [B] | ||
|} | |} | ||
| style="vertical-align:top;" |<!---Isoglobo---> | | style="vertical-align:top;" |<!---Isoglobo---> | ||
{| class="collapsible | {| class="collapsible" border="0" cellspacing="0" width="180" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
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| <big> Ganglio ( | | <big> '''Ganglio [Gg]''' (34)</big><br/> GalNAcβ'''1-4''' ''ROOT'' | ||
| <big>Isoganglio ( | | <big>'''Isoganglio [iG]''' (3)</big><br/> GalNAcβ'''1-3''' ''ROOT'' | ||
|- | |- | ||
| | | |
Revision as of 06:05, 20 January 2010
Sphingolipid (スフィンゴ脂質)
Class Overview
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Common Abbreviations よく使う略称
Cer | Ceramides | セラミド |
Sph | Sphingosine | スフィンゴシン |
Design of Sphingolipid Identifiers ID番号の設計
25-DIGIT(5+9+9+2)
L | B | S | a | a | : | x1 | x1 | y1 | z1 | z1 | w1 | w1 | c1 | c1 | : | x2 | x2 | y2 | z2 | z2 | w2 | w2 | c2 | c2 |
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Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids (Abbr. ROOT = Galβ1-4Glcβ1-Cer) | |||||||||||
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Gala [Ga] (56) Galα-4(6)Galβ1-Cer |
Globo [Gb] (31) Galα1-4 ROOT |
Isoglobo [iB] (11) Galα1-3 ROOT | |||||||||
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Ganglio [Gg] (34) GalNAcβ1-4 ROOT |
Isoganglio [iG] (3) GalNAcβ1-3 ROOT | ||||||||||
Lactoganglio (LG)
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Lacto (Lc) Glcβ1-3 ROOT | ||||||||||
Neolacto (nL) Galβ1-4GlcNAcβ1-3 ROOT |