Category:LBS: Difference between revisions
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! style="background:#efefef; text-align:center;" colspan="4"| | ! style="background:#efefef; text-align:center;" colspan="4"| | ||
Glycosphingolipids (Abbr. | Glycosphingolipids (Abbr. R = Galβ1-4Glcβ1-Cer) | ||
|- valign="top" | |- valign="top" | ||
| <big>'''Ganglio [G] | | <big>'''Ganglio''' [G] (??)</big><br/> GalNAcβ1-4R | ||
| <big>'''Lacto [L] | | <big>'''Lacto''' [L] (??)</big><br/> GlcNAcβ1-3R | ||
| <big>'''Globo [B] | | <big>'''Globo''' [B] (??)</big><br/> Galα1-4R | ||
| <big>'''Root [R] | | <big>'''Root''' [R] (??)</big><br/> derivatives of R | ||
|- | |- | ||
| style="vertical-align:top;" |<!---Ganglio---> | | style="vertical-align:top;" |<!---Ganglio---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
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|} | |} | ||
| style="vertical-align:top;" |<!---Lacto---> | | style="vertical-align:top;" |<!---Lacto---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| Lacto? '' | | Lacto? ''GlcNAcβ1-3'' R | ||
|- | |- | ||
| Lacto '' | | Lacto Galβ1-3''GlcNAcβ1-3'' R | ||
|- | |- | ||
| Neolacto | | Neolacto Galβ1-4''GlcNAcβ1-3'' R | ||
|} | |} | ||
| style="vertical-align:top;" |<!---Globo---> | | style="vertical-align:top;" |<!---Globo---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| | | [Galα1-3]<sub>n</sub> ''Galα1-4'' R | ||
|- | |- | ||
| | | Galβ1-3GalNAcβ1-3 ''Galα1-4'' R | ||
|- | |- | ||
| | | GlcNAcβ1-6GalNAcβ1-3 ''Galα1-4'' R | ||
|- | |- | ||
| | | GalNAcβ1-3 ''Galα1-4'' R | ||
|} | |} | ||
| style="vertical-align:top;" rowspan="3"|<!---Root---> | | style="vertical-align:top;" rowspan="3"|<!---Root---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| hemato | | hemato SAs (GM3,GD3,GT3) | ||
|} | |} | ||
|- | |- | ||
| <big>'''Isoganglio | | <big>'''Isoganglio''' [IG] (??)</big><br/> GalNAcβ1-3R | ||
| <big> | | <big>Lacto with β1-6 [L6] (??)</big><br/> GlcNAcβ1-6R | ||
| <big>'''Isoglobo | | <big>'''Isoglobo''' [IB] (??)</big><br/> Galα1-3R | ||
|- style="vertical-align:top;" | |- style="vertical-align:top;" | ||
| <big></big><br/> | | <big></big><br/> | ||
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| | | | ||
|} | |} | ||
| <big>'''Lactoganglio [LG] | | <big>'''Lactoganglio''' [LG]</big><br/> | ||
{| style="float:right;" | {| style="float:right;" | ||
|- | |- | ||
| | | | ||
GalNAcβ1-4<br/> | |||
GlcNAcβ1-3 | |||
| | | R | ||
|} | |} | ||
| <big>'''Isogloboganglio''' </big><br/> | | <big>'''Isogloboganglio''' [BG]</big><br/> | ||
{| style="float:right;" | {| style="float:right;" | ||
|- | |- | ||
| | | | ||
GalNAcβ1-4<br/> | |||
Galα1-3 | |||
| | | R | ||
|} | |} | ||
|} | |} | ||
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Glycosphingolipids without ROOT | Glycosphingolipids without ROOT | ||
|- valign="top" | |- valign="top" | ||
| <big> | | <big>GlucosylCer (??)</big><br/> Glcβ1-Cer | ||
| <big> | | <big>GalactosylCer (??)</big><br/> Galβ1-Cer | ||
|- | |- | ||
| style="vertical-align:top;" |<!---Glc type---> | | style="vertical-align:top;" |<!---Glc type---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd saccharides | ! style="background:#efefef; text-align:center;" | 2nd saccharides | ||
|- | |- | ||
| GlucosylCer '' | | GlucosylCer ''Glcβ1-Cer'' | ||
|- | |- | ||
| Arthro | | Arthro GlcNAcβ3-1Manβ4-1''Glcβ1-Cer'' | ||
|- | |- | ||
| Mollu | | Mollu Manα3-1Manβ4-1''Glcβ1-Cer'' | ||
|- | |- | ||
| Muco | | Muco Galβ1-4Galβ1-4''Glcβ1-Cer'' | ||
|- | |- | ||
| | | | ||
|} | |} | ||
| style="vertical-align:top;" |<!---Gala---> | | style="vertical-align:top;" |<!---Gala---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd saccharides | ! style="background:#efefef; text-align:center;" | 2nd saccharides | ||
|- | |- | ||
| Gala | | Gala Galα1-4(6)''Galβ1-Cer'' | ||
|- | |- | ||
| ??? | | ??? Galβ1-4(6)''Galβ1-Cer'' | ||
|- | |- | ||
| Spirometo | | Spirometo Galβ1-4Glcβ1-3''Galβ1-Cer'' | ||
|- | |- | ||
| | | NeuAcα2-3''Galβ1-Cer'' | ||
|} | |} | ||
|- | |||
| <big>Phospho (??)</big><br/> Ino-P-Cer | |||
| <big>Others (??) </big> | |||
|- | |||
| style="vertical-align:top;" |<!---Phospho---> | | style="vertical-align:top;" |<!---Phospho---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd saccharides | ! style="background:#efefef; text-align:center;" | 2nd saccharides | ||
| | | | ||
|} | |} | ||
| style="vertical-align:top;" |<!---Others---> | | style="vertical-align:top;" |<!---Others---> | ||
{| class="collapsible" border="0" cellspacing="0 | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd saccharides | ! style="background:#efefef; text-align:center;" | 2nd saccharides | ||
|- | |- |
Revision as of 07:28, 22 January 2010
Sphingolipid (スフィンゴ脂質)
Class Overview
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Common Abbreviations よく使う略称
Cer | Ceramides | セラミド |
Sph | Sphingosine | スフィンゴシン |
Design of Sphingolipid Identifiers ID番号の設計
25-DIGIT(5+9+9+2)
L | B | S | a | a | : | x1 | x1 | y1 | z1 | z1 | w1 | w1 | c1 | c1 | : | x2 | x2 | y2 | z2 | z2 | w2 | w2 | c2 | c2 |
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Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids (Abbr. R = Galβ1-4Glcβ1-Cer) | |||||||||||||||||
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Ganglio [G] (??) GalNAcβ1-4R |
Lacto [L] (??) GlcNAcβ1-3R |
Globo [B] (??) Galα1-4R |
Root [R] (??) derivatives of R | ||||||||||||||
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Isoganglio [IG] (??) GalNAcβ1-3R |
Lacto with β1-6 [L6] (??) GlcNAcβ1-6R |
Isoglobo [IB] (??) Galα1-3R | |||||||||||||||
Lactoganglio [LG]
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Isogloboganglio [BG]
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Glycosphingolipids without ROOT | ||||||||||||
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GlucosylCer (??) Glcβ1-Cer |
GalactosylCer (??) Galβ1-Cer | |||||||||||
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Phospho (??) Ino-P-Cer |
Others (??) | |||||||||||
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