Category:LBS: Difference between revisions
Line 167: | Line 167: | ||
| style="vertical-align:top;" |<!---Ganglio---> | | style="vertical-align:top;" |<!---Ganglio---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | | ! style="background:#efefef; text-align:center;" | 3rd saccharide | ||
|- | |- | ||
| | | | ||
Line 175: | Line 175: | ||
| style="vertical-align:top;" |<!---Lacto---> | | style="vertical-align:top;" |<!---Lacto---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | | ! style="background:#efefef; text-align:center;" | 3rd saccharide | ||
|- | |- | ||
| Lacto? ''GlcNAcβ1-3'' R | | Lacto? ''GlcNAcβ1-3'' R | ||
Line 185: | Line 185: | ||
| style="vertical-align:top;" |<!---Globo---> | | style="vertical-align:top;" |<!---Globo---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | | ! style="background:#efefef; text-align:center;" | 3rd saccharide | ||
|- | |- | ||
| [Galα1-3]<sub>n</sub> ''Galα1-4'' R | | [Galα1-3]<sub>n</sub> ''Galα1-4'' R | ||
Line 197: | Line 197: | ||
| style="vertical-align:top;" rowspan="3"|<!---Root---> | | style="vertical-align:top;" rowspan="3"|<!---Root---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | | ! style="background:#efefef; text-align:center;" | structure | ||
|- | |- | ||
| hemato SAs (GM3,GD3,GT3) | | hemato SAs (GM3,GD3,GT3) | ||
Line 241: | Line 241: | ||
| style="vertical-align:top;" |<!---Glc type---> | | style="vertical-align:top;" |<!---Glc type---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd | ! style="background:#efefef; text-align:center;" | 2nd saccharide | ||
|- | |- | ||
| GlucosylCer ''Glcβ1-Cer'' | | GlucosylCer ''Glcβ1-Cer'' | ||
Line 255: | Line 255: | ||
| style="vertical-align:top;" |<!---Gala---> | | style="vertical-align:top;" |<!---Gala---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd | ! style="background:#efefef; text-align:center;" | 2nd saccharide | ||
|- | |- | ||
| Gala Galα1-4(6)''Galβ1-Cer'' | | Gala Galα1-4(6)''Galβ1-Cer'' | ||
Line 271: | Line 271: | ||
| style="vertical-align:top;" |<!---Phospho---> | | style="vertical-align:top;" |<!---Phospho---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd | ! style="background:#efefef; text-align:center;" | 2nd saccharide | ||
| | | | ||
|} | |} | ||
| style="vertical-align:top;" |<!---Others---> | | style="vertical-align:top;" |<!---Others---> | ||
{| class="collapsible" border="0" cellspacing="0" | {| class="collapsible" border="0" cellspacing="0" | ||
! style="background:#efefef; text-align:center;" | 2nd | ! style="background:#efefef; text-align:center;" | 2nd saccharide | ||
|- | |- | ||
| '' | | '' |
Revision as of 07:40, 22 January 2010
Sphingolipid (スフィンゴ脂質)
Class Overview
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
|
スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
|
Common Abbreviations よく使う略称
Cer | Ceramides | セラミド |
Sph | Sphingosine | スフィンゴシン |
Design of Sphingolipid Identifiers ID番号の設計
25-DIGIT(5+9+9+2)
L | B | S | a | a | : | x1 | x1 | y1 | z1 | z1 | w1 | w1 | c1 | c1 | : | x2 | x2 | y2 | z2 | z2 | w2 | w2 | c2 | c2 |
|
|
Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
---|---|---|
(0 pages) | (0 pages) | (0 pages) | (0 pages) |
(0 pages) | (0 pages) | (0 pages) | (0 pages) |
(0 pages) | (0 pages) | (0 pages) | (0 pages) |
(0 pages) | (0 pages) | (0 pages) | (0 pages) |
(0 pages) | (0 pages) | (0 pages) | (0 pages) |
(0 pages) | (0 pages) | (0 pages) | (0 pages) |
Polysaccharide Chain
Glycosphingolipids (Abbr. R = Galβ1-4Glcβ1-Cer) | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ganglio [G] (??) GalNAcβ1-4R |
Lacto [L] (??) GlcNAcβ1-3R |
Globo [B] (??) Galα1-4R |
Root [R] (??) derivatives of R | ||||||||||||||
|
|
|
| ||||||||||||||
Isoganglio [IG] (??) GalNAcβ1-3R |
Lacto with β1-6 [L6] (??) GlcNAcβ1-6R |
Isoglobo [IB] (??) Galα1-3R | |||||||||||||||
Lactoganglio [LG]
|
Isogloboganglio [BG]
|
Glycosphingolipids without ROOT | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
GlucosylCer (??) Glcβ1-Cer |
GalactosylCer (??) Galβ1-Cer | |||||||||||
|
| |||||||||||
Phospho (??) Ino-P-Cer |
Others (??) | |||||||||||
|
|