Category:LBS: Difference between revisions
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===Sugar Code=== | ===Sugar Code=== | ||
<small>"I" and "O" are not used to avoid confusion with "1" or "0".</small> | |||
{| class="wikitable" style="text-align:center" | {| class="wikitable" style="text-align:center" | ||
! code | ! code | ||
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| '''0''' || no sugar | | '''0''' || no sugar | ||
| '''A''' || other <span style="color:gold">Galactose (<b>Gal</b>)</span><br/> including methylation | | '''A''' || other <span style="color:gold">Galactose (<b>Gal</b>)</span><br/> including methylation | ||
| '''L''' || < | | '''L''' || Rhamnose (<b>Rha</b>) or pentose sugars (<b>Ara, Xyl</b>) | ||
|- | |- | ||
| '''1''' || {{LBS/FormatSugar|Gala1-3}} | | '''1''' || {{LBS/FormatSugar|Gala1-3}} | ||
| '''B''' || | | '''B''' || Other ''N''-acetyl <span style="color:gold">galactosamine (<b>GalNAc</b>)</span> or <br/> <span style="color:blue">glucosamine (<b>GlcNAc</b>)</span> | ||
| '''M''' || <span style="color: | | '''M''' || <span style="color:green">Mannose (<b>Man</b>)</span> | ||
|- | |- | ||
| '''2''' || {{LBS/FormatSugar|Gala1-4}} | | '''2''' || {{LBS/FormatSugar|Gala1-4}} | ||
| '''C''' || | | '''C''' || <span style="color:gold">Galactosamine (<b>GalN</b>)</span> or<br/> <span style="color:blue">Glucosamine (<b>GlcN</b>)</span> | ||
| '''N''' || | | '''N''' || <span style="color:pink">Neuraminic acids (<b>NeuAc, NeuGc, NeuNH, KDN</b>)</span> | ||
|- | |- | ||
| '''3''' || {{LBS/FormatSugar|Gala1-6}} | | '''3''' || {{LBS/FormatSugar|Gala1-6}} | ||
| '''D''' || {{LBS/FormatSugar|GlcNAcb1- | | '''D''' || {{LBS/FormatSugar|GlcNAcb1-3}} | ||
| '''P''' || phosphocholine (<b>PC</b>), phosphate (<b>HPO3</b>), sulphate (<b>HSO3</b>), and ethylene (<b>2C=CH</b>) | | '''P''' || phosphocholine (<b>PC</b>), phosphate (<b>HPO3</b>), sulphate (<b>HSO3</b>), and ethylene (<b>2C=CH</b>) | ||
|- | |- | ||
| '''4''' || {{LBS/FormatSugar|Galb1-3}} | | '''4''' || {{LBS/FormatSugar|Galb1-3}} | ||
| '''E''' || | | '''E''' || {{LBS/FormatSugar|GlcNAcb1-4}} | ||
| '''Q''' || Aminoethylphosphate (<b>AEPn, MAEPr, EtnP</b>) | | '''Q''' || Aminoethylphosphate (<b>AEPn, MAEPr, EtnP</b>) | ||
|- | |- | ||
| '''5''' || {{LBS/FormatSugar|Galb1-4}} | | '''5''' || {{LBS/FormatSugar|Galb1-4}} | ||
| '''F''' || | | '''F''' || {{LBS/FormatSugar|GlcNAcb1-6}} | ||
| || | | || | ||
|- | |- | ||
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|- | |- | ||
| '''7''' || {{LBS/FormatSugar|GalNAcb1-3}} | | '''7''' || {{LBS/FormatSugar|GalNAcb1-3}} | ||
| '''H''' || <span style="color: | | '''H''' || <span style="color:blue">Glucuronic acid (<b>GlcA</b>)</span> | ||
| || | | || | ||
|- | |- | ||
| '''8''' || {{LBS/FormatSugar|GalNAcb1-4}} | | '''8''' || {{LBS/FormatSugar|GalNAcb1-4}} | ||
| '''J''' || <span style="color:purple">Inositol (<b>Ins</b>)</span> | | '''J''' || <span style="color:purple">Inositol (<b>Ins</b>)</span> | ||
| || | | '''Y''' || invertebrates | ||
|- | |- | ||
| '''9''' || {{LBS/FormatSugar|GalNAcb1-6}} | | '''9''' || {{LBS/FormatSugar|GalNAcb1-6}} | ||
| '''K''' || <span style="color:red">Fucose (<b>Fuc</b>)</span> | | '''K''' || <span style="color:red">Fucose (<b>Fuc</b>)</span> | ||
| || | | '''Z''' || vertebrates | ||
|} | |} | ||
Revision as of 05:52, 7 March 2011
Sphingolipid
Class Overview
Sphingosine & Ceramide
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Abbreviations
Template:BilingualID番号 (ページタイトル) の設計
L | B | S | x | s1 | s2 | s3 | n1 | n2 | y | c1 | c2 |
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Sugar Code
"I" and "O" are not used to avoid confusion with "1" or "0".
code | sugar | code | sugar | code | sugar |
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0 | no sugar | A | other Galactose (Gal) including methylation |
L | Rhamnose (Rha) or pentose sugars (Ara, Xyl) |
1 | Galα1-3 | B | Other N-acetyl galactosamine (GalNAc) or glucosamine (GlcNAc) |
M | Mannose (Man) |
2 | Galα1-4 | C | Galactosamine (GalN) or Glucosamine (GlcN) |
N | Neuraminic acids (NeuAc, NeuGc, NeuNH, KDN) |
3 | Galα1-6 | D | GlcNAcβ1-3 | P | phosphocholine (PC), phosphate (HPO3), sulphate (HSO3), and ethylene (2C=CH) |
4 | Galβ1-3 | E | GlcNAcβ1-4 | Q | Aminoethylphosphate (AEPn, MAEPr, EtnP) |
5 | Galβ1-4 | F | GlcNAcβ1-6 | ||
6 | Galβ1-6 | G | Other Glucose (Glc) | ||
7 | GalNAcβ1-3 | H | Glucuronic acid (GlcA) | ||
8 | GalNAcβ1-4 | J | Inositol (Ins) | Y | invertebrates |
9 | GalNAcβ1-6 | K | Fucose (Fuc) | Z | vertebrates |
Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids (Abbr. R = Galβ1-4Glcβ1-Cer) | |||||||||||||||||
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Ganglio [Gg] (??) GalNAcβ1-4R |
Lacto [Lc] (??) GlcNAcβ1-3R |
Globo [Gb] (??) Galα1-4R |
Root [R] (??) derivatives of R | ||||||||||||||
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Isoganglio [IG] (??) GalNAcβ1-3R |
Lacto with β1-6 [L6] (??) GlcNAcβ1-6R |
Isoglobo [IB] (??) Galα1-3R | |||||||||||||||
Lactoganglio [LG]
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Isogloboganglio [BG]
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Glycosphingolipids without ROOT | ||||||||||||
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Glc-Cer (??) Glcβ1-Cer |
Gal-Cer (??) Galβ1-Cer | |||||||||||
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Phospho (??) Ino-P-Cer |
Others (??) | |||||||||||
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