Category:LBS: Difference between revisions
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<td style="background-color:yellowgreen;" width=15px align="center"><big>B</big> | <td style="background-color:yellowgreen;" width=15px align="center"><big>B</big> | ||
<td style="background-color:darkseagreen;" width=15px align="center"><big>S</big> | <td style="background-color:darkseagreen;" width=15px align="center"><big>S</big> | ||
<td style="background-color: | <td style="background-color:firebrick;" width=15px align="center"><big>''H/L''</big> | ||
<td style="background-color:Blue; color:white" width=15px align="center"><big>''s1''</big> | <td style="background-color:Blue; color:white" width=15px align="center"><big>''s1''</big> | ||
<td style="background-color:Blue; color:white" width=15px align="center"><big>''s2''</big> | <td style="background-color:Blue; color:white" width=15px align="center"><big>''s2''</big> | ||
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</center> | </center> | ||
{{Twocolumn| | {{Twocolumn| | ||
* | * '''H''' for vertebrates and '''L''' for invertebrates | ||
* '''s1 ∼ s3''' ... Structure code | * '''s1 ∼ s3''' ... Structure code | ||
: The 1<sup>st</sup> letter '''s1''': | : The 1<sup>st</sup> letter '''s1''': | ||
:: '''Z''' for {{LBS/FormatSugar|Galb1-4Glcb1-1bCer}} | :: '''Z''' for {{LBS/FormatSugar|Galb1-4Glcb1-1bCer}} | ||
:: '''Y''' (''Arthro'') for {{LBS/FormatSugar|GlcNAcb1-3Manb1-4Glcb1-1Cer}} | :: '''Y''' (''Arthro'') for {{LBS/FormatSugar|GlcNAcb1-3Manb1-4Glcb1-1Cer}} | ||
:: '''0''' ∼ '''Q''' | :: For others, '''0''' ∼ '''Q''' of the 1<sup>st</sup> sugar | ||
: The 2<sup>nd</sup> and 3<sup>rd</sup> letters '''s2''' and '''s3''': | : The 2<sup>nd</sup> and 3<sup>rd</sup> letters '''s2''' and '''s3''': | ||
:: '''0''' to '''Q''' for the 3<sup>rd</sup> and 4<sup>th</sup> sugars for '''Z''' class | :: '''0''' to '''Q''' for the 3<sup>rd</sup> and 4<sup>th</sup> sugars for '''Z''' class |
Revision as of 07:22, 7 March 2011
Sphingolipid
Class Overview
Sphingosine & Ceramide
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Abbreviations
Template:BilingualID番号 (ページタイトル) の設計
L | B | S | H/L | s1 | s2 | s3 | n1 | n2 | y | c1 | c2 |
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Sugar Code
"I" and "O" are not used to avoid confusion with "1" or "0".
code | sugar | code | sugar | code | sugar |
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0 | no sugar | A | other Galactose (Gal) including methylation |
L | Rhamnose (Rha) or pentose sugars (Ara, Xyl) |
1 | Galα1-3 | B | Other N-acetyl galactosamine (GalNAc) or glucosamine (GlcNAc) |
M | Mannose (Man) |
2 | Galα1-4 | C | Galactosamine (GalN) or Glucosamine (GlcN) |
N | Neuraminic acids (NeuAc, NeuGc, NeuNH, KDN) |
3 | Galα1-6 | D | GlcNAcβ1-3 | P | phosphocholine (PC), phosphate (HPO3), sulphate (HSO3), and ethylene (2C=CH) |
4 | Galβ1-3 | E | GlcNAcβ1-4 | Q | Aminoethylphosphate (AEPn, MAEPr, EtnP) |
5 | Galβ1-4 | F | GlcNAcβ1-6 | ||
6 | Galβ1-6 | G | Other Glucose (Glc) | ||
7 | GalNAcβ1-3 | H | Glucuronic acid (GlcA) | ||
8 | GalNAcβ1-4 | J | Inositol (Ins) | Y | invertebrates |
9 | GalNAcβ1-6 | K | Fucose (Fuc) | Z | vertebrates |
Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids (Abbr. R = Galβ1-4Glcβ1-Cer) | |||||||||||||||||
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Ganglio [Gg] (??) GalNAcβ1-4R |
Lacto [Lc] (??) GlcNAcβ1-3R |
Globo [Gb] (??) Galα1-4R |
Root [R] (??) derivatives of R | ||||||||||||||
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Isoganglio [IG] (??) GalNAcβ1-3R |
Lacto with β1-6 [L6] (??) GlcNAcβ1-6R |
Isoglobo [IB] (??) Galα1-3R | |||||||||||||||
Lactoganglio [LG]
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Isogloboganglio [BG]
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Glycosphingolipids without ROOT | ||||||||||||
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Glc-Cer (??) Glcβ1-Cer |
Gal-Cer (??) Galβ1-Cer | |||||||||||
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Phospho (??) Ino-P-Cer |
Others (??) | |||||||||||
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