Category:LBS: Difference between revisions
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==Polysaccharide Chain== | ==Polysaccharide Chain== | ||
<center> | <center> | ||
{| border="1" cellpadding="0" cellspacing="0" style="text-align:right;" | {| border="1" cellpadding="0" cellspacing="0" style="text-align:right;" | ||
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! style="background:#efefef; text-align:center;" colspan="3"| | ! style="background:#efefef; text-align:center;" colspan="3"| | ||
Glycosphingolipids | Glycosphingolipids without ROOT | ||
|- valign="top" | |- valign="top" | ||
| <big>''' | | <big>'''Gala''' (??)</big><br/> '''Galβ1-'''Cer | ||
| <big>''' | | <big>'''??? ''' (??)</big><br/> '''Glcβ1-'''Cer | ||
| <big> | | <big>Others (??) </big> | ||
|- | |- | ||
| style="vertical-align:top;" |<!---Gala---> | | style="vertical-align:top;" |<!---Gala---> | ||
{| class="collapsible" border="0" cellspacing="0" width="180" | {| class="collapsible" border="0" cellspacing="0" width="180" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd saccharides | ||
|- | |||
| Gala '''Galα1-4(6)''' | |||
|- | |||
| ??? '''Galβ1-4(6)''' | |||
|- | |||
| Spirometo '''Galb1-4Glcb1-3''' | |||
|- | |||
| '''SO<sub>3</sub>H-3''' | |||
|- | |||
| '''NeuAcα3-1''' | |||
|} | |||
| style="vertical-align:top;" |<!---Glc type---> | |||
{| class="collapsible" border="0" cellspacing="0" width="180" | |||
! style="background:#efefef; text-align:center;" | 2nd saccharides | |||
|- | |||
| Arthro '''GlcNAcβ3-1Manβ4-1''' | |||
|- | |||
| Mollu '''Manα3-1Manβ4-1''' | |||
|- | |||
| Muco '''Galβ1-4Galβ1-4''' | |||
|- | |||
| | |||
|} | |||
| style="vertical-align:top;" |<!---Others---> | |||
{| class="collapsible" border="0" cellspacing="0" width="180" | |||
! style="background:#efefef; text-align:center;" | 2nd saccharides | |||
|- | |- | ||
| | | '' | ||
|- | |- | ||
| | | | ||
|} | |} | ||
|} | |||
</center> | |||
<center> | |||
{| border="1" cellpadding="0" cellspacing="0" style="text-align:right;" | |||
|+ Table 1. Glycosphingolipids and Phosphosphingolipids | |||
|- | |||
! style="background:#efefef; text-align:center;" colspan="3"| | |||
Glycosphingolipids (Abbr. ROOT = Galβ1-4Glcβ1-Cer) | |||
|- valign="top" | |||
| <big>''' Globo [Gb]''' (??)</big><br/> '''Galα1-4''' ''ROOT'' | |||
| <big> '''Ganglio [Gg]''' (??)</big><br/> '''GalNAcβ1-4''' ''ROOT'' | |||
| <big> '''Lacto? [??]''' (??)</big><br/> '''GlcNAcβ1-3''' ''ROOT'' | |||
|- | |||
| style="vertical-align:top;" |<!---Globo---> | | style="vertical-align:top;" |<!---Globo---> | ||
{| class="collapsible" border="0" cellspacing="0" width="180" | {| class="collapsible" border="0" cellspacing="0" width="180" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| ...-[Galα1-3]<sub>n</sub> & | | ...-[Galα1-3]<sub>n</sub> | ||
|- | |||
| ...-Galb1-3GalNAcβ1-3 | |||
|- | |||
| ...-GlcNAcβ1-6GalNAcβ1-3 | |||
|- | |||
| ...-GalNAcβ1-3 | |||
|} | |||
| style="vertical-align:top;" |<!---Ganglio---> | |||
{| class="collapsible" border="0" cellspacing="0" width="180" | |||
! style="background:#efefef; text-align:center;" | 2nd class | |||
|- | |- | ||
| | | | ||
|- | |- | ||
| | | | ||
|- | |- | ||
| | | | ||
|} | |} | ||
| style="vertical-align:top;" |<!--- | | style="vertical-align:top;" |<!---???---> | ||
{| class="collapsible" border="0" cellspacing="0" width="180" | {| class="collapsible" border="0" cellspacing="0" width="180" | ||
! style="background:#efefef; text-align:center;" | 2nd class | ! style="background:#efefef; text-align:center;" | 2nd class | ||
|- | |- | ||
| Lacto '''Galβ1-3''' | |||
|- | |||
| Neolacto '''Galβ1-4''' | |||
|- | |||
| ... | |||
|} | |} | ||
|- | |- | ||
| <big>'''Isoglobo [iB]''' (??)</big><br/> '''Galα1-3''' ''ROOT'' | |||
| <big> | | <big>'''Isoganglio [iG]''' (??)</big><br/> '''GalNAcβ1-3''' ''ROOT'' | ||
| <big>'''Isoganglio [iG]''' ( | | <big>Lactoganglio (LG)</big><br/> | ||
| <big>Lactoganglio (LG)</big><br/> | |||
{| style="float:right;" | {| style="float:right;" | ||
|- | |- | ||
| | | | ||
GalNAcβ | '''GalNAcβ1-4'''<br/> | ||
GlcNAcβ | '''GlcNAcβ1-3''' | ||
| ''ROOT'' | | ''ROOT'' | ||
|} | |} | ||
|} | |} | ||
</center> | </center> |
Revision as of 05:10, 21 January 2010
Sphingolipid (スフィンゴ脂質)
Class Overview
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Common Abbreviations よく使う略称
Cer | Ceramides | セラミド |
Sph | Sphingosine | スフィンゴシン |
Design of Sphingolipid Identifiers ID番号の設計
25-DIGIT(5+9+9+2)
L | B | S | a | a | : | x1 | x1 | y1 | z1 | z1 | w1 | w1 | c1 | c1 | : | x2 | x2 | y2 | z2 | z2 | w2 | w2 | c2 | c2 |
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Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids without ROOT | ||||||||||||||||
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Gala (??) Galβ1-Cer |
??? (??) Glcβ1-Cer |
Others (??) | ||||||||||||||
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Glycosphingolipids (Abbr. ROOT = Galβ1-4Glcβ1-Cer) | |||||||||||||||
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Globo [Gb] (??) Galα1-4 ROOT |
Ganglio [Gg] (??) GalNAcβ1-4 ROOT |
Lacto? [??] (??) GlcNAcβ1-3 ROOT | |||||||||||||
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Isoglobo [iB] (??) Galα1-3 ROOT |
Isoganglio [iG] (??) GalNAcβ1-3 ROOT |
Lactoganglio (LG)
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