LBF20107PG19: Difference between revisions

Latest revision as of 03:20, 10 November 2010

Upper classes: LB LBF

8-iso Prostaglandin E₁

Structural Information
	9-Oxo-(11α,15S) -dihydroxy- (8β) -prost-trans-13-en-1-oic acid
	8-iso Prostaglandin E₁ 9-Oxo-(11α,15S) -dihydroxy- (8β) -prost-13E-en-1-oic acid

Formula	C20H34O5
Exact Mass	354.240624198
Average Mass	354.48096000000004
SMILES	`C(CC[C@H](O)C=C[C@H]([C@@H]1CCCCCCC(O)=O)[C@@H](CC1=O)O)CC`
Physicochemical Information






	8-iso PGE1 is an isoprostane which is found in human semen at the concentration of 7 mu g/ml. Taylor_PL


	8-iso PGE1 is reported as a pulmonary vasoconstrictor in anesthetized dogs at similar concentration to PGF2 alpha . Nakano_J et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20107PG19	See above.	Nakano_J et al. 1970
n.a.	LBF20107PG19	See above.	Taylor_PL 1979

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
@@ Line 4: / Line 6: @@
 |LipidBank=XPR1777
 |LipidMaps=-
-|SysName=9-oxo-11a,15S-dihydroxy- (8b) -prost-13E-en-1-oic acid
+|SysName=9-Oxo-(11alpha,15S) -dihydroxy- (8beta) -prost-trans-13-en-1-oic acid
-|Common Name=&&8-iso Prostaglandin E1&&
+|Common Name=&&8-iso Prostaglandin E_1&&9-Oxo-(11alpha,15S) -dihydroxy- (8beta) -prost-13E-en-1-oic acid&&
+|Source=8-iso PGE1 is an isoprostane which is found in human semen at the concentration of 7  mu g/ml.[[Reference:Taylor_PL:,Prostaglandins,1979,17,259|{{RelationTable/GetFirstAuthor|Reference:Taylor_PL:,Prostaglandins,1979,17,259}}]]
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=8-iso PGE1 is reported as a pulmonary vasoconstrictor in anesthetized dogs at similar concentration to PGF2 alpha .[[Reference:Nakano_J:Kessinger_JM:,Proc. Soc. Exp. Biol. Med.,1970,133,1314|{{RelationTable/GetFirstAuthor|Reference:Nakano_J:Kessinger_JM:,Proc. Soc. Exp. Biol. Med.,1970,133,1314}}]]
 }}
+{{Lipid/Footer}}