LBF20207PG28: Difference between revisions
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{{Lipid/Header}} | |||
{{Hierarchy|{{PAGENAME}}}} | {{Hierarchy|{{PAGENAME}}}} | ||
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|LipidBank=XPR1711 | |LipidBank=XPR1711 | ||
|LipidMaps=LMFA03010148 | |LipidMaps=LMFA03010148 | ||
|SysName=9- | |SysName=9-Oxo- (11alpha,15S) -dihydroxy-prosta- (trans-5,trans-13) -dien-1-oic acid | ||
|Common Name=&&5-trans Prostaglandin E_2&& | |Common Name=&&5-trans Prostaglandin E_2&&9-Oxo- (11alpha,15S) -dihydroxy-prosta- (5E,13E) -dien-1-oic acid&& | ||
|Source=5-trans PGE2 is naturally produced by some gorgonian corals and is also a common impurity in commercial lots of PGE1. | |||
|Chemical Synthesis= | |||
|Metabolism= | |||
|Biological Activity=5-trans PGE2 has 18 times potency in activating adenylate cyclase compared to PGE2.[[Reference:Hensby_CN:MacDermot_J:,Biochem. Soc. Trans.,1979,7,1302|{{RelationTable/GetFirstAuthor|Reference:Hensby_CN:MacDermot_J:,Biochem. Soc. Trans.,1979,7,1302}}]] 5-trans PGE2 accelerates fibrinolysis by enhancing plasminogen activation mediated dby tissue-type plasminogen activator.[[Reference:Shimokawa_M:Urano_T:Kinoshita_T:,Biochim. Biophys. Acta,1992,1137,317|{{RelationTable/GetFirstAuthor|Reference:Shimokawa_M:Urano_T:Kinoshita_T:,Biochim. Biophys. Acta,1992,1137,317}}]] And it also inhibits platelet | |||
}} | }} | ||
{{Lipid/Footer}} | |||
Latest revision as of 08:31, 21 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | XPR1711 |
| LipidMaps | LMFA03010148 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20207PG28 |
| 5-trans Prostaglandin E2 | |
|---|---|
| |
| Structural Information | |
| 9-Oxo- (11α,15S) -dihydroxy-prosta- (trans-5,trans-13) -dien-1-oic acid | |
| |
| Formula | C20H32O5 |
| Exact Mass | 352.224974134 |
| Average Mass | 352.46508 |
| SMILES | C(CC[C@@H](O)C=C[C@H]([C@H]1CC=CCCCC(O)=O)[C@@H](CC1=O)O)CC |
| Physicochemical Information | |
| 5-trans PGE2 is naturally produced by some gorgonian corals and is also a common impurity in commercial lots of PGE1. | |
| 5-trans PGE2 has 18 times potency in activating adenylate cyclase compared to PGE2. Hensby_CN et al. 5-trans PGE2 accelerates fibrinolysis by enhancing plasminogen activation mediated dby tissue-type plasminogen activator. Shimokawa_M et al. And it also inhibits platelet | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | |||||||||||||||
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