LBF20406AM11: Difference between revisions

Revision as of 12:19, 9 September 2010

Upper classes: LB LBF

N-Amylarachidohoylamide

Structural Information
	N- (5-cis,8-cis,11-cis,14-cis) -Eicosatetraenoylamine
	N-Amylarachidohoylamide N- (5Z,8Z,11Z,14Z) -EicosatetraenoylamineN-Amylarachidohoylamide

Formula	C25H43NO
Exact Mass	373.334465003
Average Mass	373.61505999999997
SMILES	`C(CCCNC(CCCC=CCC=CCC=CCC=CCCCCC)=O)C`
Physicochemical Information
	colorless oil Sheskin_T et al.






	This compound was synthesized from arachidonoylchloride and amylamine.Yield 70 % Sheskin_T et al.

	Binding of this compound to the brain cannabinoid receptor (CBl),Ki(nM)>l000 Sheskin_T et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra	¹H NMR (CDCl3) δ 5.70 (br s lH), 5.23-5.33 (m, 8H), 3.15 (q, J=3Hz, 2H), 2.71-2.77(m, 6H), 1.97-2.16 (m, 6H), 1.58-1.68 (m, 2H), 1.18-1.42 (m, l2H), 0.79-0.85 (m, 6H). Sheskin_Tet al.
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20406AM11	See above.	Sheskin_T et al. 1997

@@ Line 6: / Line 6: @@
 |LipidBank=XPR7027
 |LipidMaps=LMFA08020013
-|SysName=N-Amylarachidohoylamide
+|SysName=N- (5-cis,8-cis,11-cis,14-cis) -Eicosatetraenoylamine
-|Common Name=&&N-Amylarachidohoylamide&&
+|Common Name=&&N-Amylarachidohoylamide&&N- (5Z,8Z,11Z,14Z) -EicosatetraenoylamineN-Amylarachidohoylamide&&
 |Melting Point=colorless oil [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
 |NMR Spectra=^1 H NMR (CDCl3)  delta 5.70 (br s lH), 5.23-5.33 (m, 8H), 3.15 (q, J=3Hz, 2H), 2.71-2.77(m, 6H), 1.97-2.16 (m, 6H), 1.58-1.68 (m, 2H), 1.18-1.42 (m, l2H), 0.79-0.85 (m, 6H). [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]