LBF20406AM42: Difference between revisions
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|LipidBank=XPR7044 | |LipidBank=XPR7044 | ||
|LipidMaps=LMFA08020030 | |LipidMaps=LMFA08020030 | ||
|SysName= | |SysName=dl-N- (1-Methyl-2-hydroxy-2-phenylethyl) - (cis-5,cis-8,cis-11,cis-14) -eicosatetraenoylamine | ||
|Common Name=&&(+-) -N- (1- | |Common Name=&&N- (1-Methyl-2-hydroxy-2-phenylethyl) -arachidonoylamide&&(+-) -N- (1-Methyl-2-hydroxy-2-phenylethyl) - (5Z,8Z,11Z,14Z) -eicosatetraenoylamine&& | ||
|Melting Point=colorless oil [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | |Melting Point=colorless oil [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | ||
|NMR Spectra= | |NMR Spectra=^1 H NMR (CDCl3) delta 7.27-7.35 (m, 5H), 5.54 (br s , lH), 5.63-5.41 (m, 8H), 4.84 (br s, lH),4.31-4.36 (m, lH), 3.60 (br s, lH), 2.78-2.85 (m, 6H), 2.01-2.22 (m, 6H), 1.67-1.77 (m, 2H),1.25-1.37 (m, 6H), 1.01 (d, J=7.l Hz, 3H), 0.89 (t, J=7.l Hz, 3H). [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | ||
|Source= | |Source= | ||
|Chemical Synthesis=This compound was synthesized from arachidonoylchloride and (±)phenylpropanolamine.Yield 67 %. [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | |Chemical Synthesis=This compound was synthesized from arachidonoylchloride and (±)phenylpropanolamine.Yield 67 %. [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | ||
Latest revision as of 04:50, 21 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | XPR7044 |
| LipidMaps | LMFA08020030 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406AM42 |
| N- (1-Methyl-2-hydroxy-2-phenylethyl) -arachidonoylamide | |
|---|---|
| |
| Structural Information | |
| dl-N- (1-Methyl-2-hydroxy-2-phenylethyl) - (cis-5,cis-8,cis-11,cis-14) -eicosatetraenoylamine | |
| |
| Formula | C29H43NO2 |
| Exact Mass | 437.329379625 |
| Average Mass | 437.65725999999995 |
| SMILES | C(=CCC=CCC=CCCCC(=O)NC(C(O)c(c1)cccc1)C)CC=CCCCCC |
| Physicochemical Information | |
| colorless oil Sheskin_T et al. | |
| This compound was synthesized from arachidonoylchloride and (±)phenylpropanolamine.Yield 67 %. Sheskin_T et al. | |
| Binding to the brain cannabinoid receptor (CBl), Ki(nM)>1000 Sheskin_T et al. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | |
| IR Spectra | |
| NMR Spectra | 1H NMR (CDCl3) δ 7.27-7.35 (m, 5H), 5.54 (br s , lH), 5.63-5.41 (m, 8H), 4.84 (br s, lH),4.31-4.36 (m, lH), 3.60 (br s, lH), 2.78-2.85 (m, 6H), 2.01-2.22 (m, 6H), 1.67-1.77 (m, 2H),1.25-1.37 (m, 6H), 1.01 (d, J=7.l Hz, 3H), 0.89 (t, J=7.l Hz, 3H). SheskinTet al. |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | ||||||||||
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