LBF20406HO12: Difference between revisions
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{{Metabolite | {{Metabolite | ||
|LipidBank=DFA8130 | |LipidBank=DFA8130 | ||
|LipidMaps= | |LipidMaps=LMFA03060021 | ||
|SysName=8R- | |SysName=8R-Hydroxy- (cis-5,trans-9,cis-11,cis-14) -eicosatetraenoic acid | ||
|Common Name=&&8R- | |Common Name=&&8R-Hydroxy- (5Z,9E,11Z,14Z) -eicosatetraenoic acid&& | ||
|UV Spectra= | |UV Spectra= lambda max: 237nm epsilon : 27,000 | ||
|Source=8(R)-HETE is a metabolite of arachidonic acid by the 8-lipoxygenase pathway in marine organisms [[Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040|{{RelationTable/GetFirstAuthor|Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040}}]][[Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829|{{RelationTable/GetFirstAuthor|Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829}}]] | |Source=8(R)-HETE is a metabolite of arachidonic acid by the 8-lipoxygenase pathway in marine organisms [[Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040|{{RelationTable/GetFirstAuthor|Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040}}]][[Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829|{{RelationTable/GetFirstAuthor|Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829}}]]. | ||
|Chemical Synthesis= | |Chemical Synthesis= | ||
|Metabolism=The precursor of 8(R)-HETE, 8(R)-HpETE, is the putative intermediate in the biosynthesis of marine prostaglandins via the allene oxide synthase pathway.[[Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829|{{RelationTable/GetFirstAuthor|Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829}}]]; | |Metabolism=The precursor of 8(R)-HETE, 8(R)-HpETE, is the putative intermediate in the biosynthesis of marine prostaglandins via the allene oxide synthase pathway.[[Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829|{{RelationTable/GetFirstAuthor|Reference:Brash_AR:Baertschi_SW:Ingram_CD:Harris_TM:,J. Biol. Chem.,1987,262,15829}}]]. | ||
|Symbol=8(R)-HETE | |||
|Biological Activity=8(R)-HETE induces maturation of starfish oocytes at a concentration of 0.071 μ M [[Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040|{{RelationTable/GetFirstAuthor|Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040}}]]. This activity if neglible in the 8(S)-enantiomer [[Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040|{{RelationTable/GetFirstAuthor|Reference:Meijer_L:Brash_AR:Bryant_RW:Ng_K:Maclouf_J:Sprecher_H:,J. Biol. Chem.,1986,261,17040}}]]. | |||
}} | }} | ||
{{Lipid/Footer}} | {{Lipid/Footer}} | ||
Latest revision as of 07:26, 21 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | DFA8130 |
| LipidMaps | LMFA03060021 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406HO12 |
| 8R-Hydroxy- (5Z,9E,11Z,14Z) -eicosatetraenoic acid | |
|---|---|
| |
| Structural Information | |
| 8R-Hydroxy- (cis-5,trans-9,cis-11,cis-14) -eicosatetraenoic acid | |
| |
| 8(R)-HETE | |
| Formula | C20H32O3 |
| Exact Mass | 320.23514489 |
| Average Mass | 320.46628 |
| SMILES | C(CC=CCC=CC=C[C@@H](CC=CCCCC(O)=O)O)CCC |
| Physicochemical Information | |
| 8(R)-HETE is a metabolite of arachidonic acid by the 8-lipoxygenase pathway in marine organisms Meijer_L et al. Brash_AR et al.. | |
| The precursor of 8(R)-HETE, 8(R)-HpETE, is the putative intermediate in the biosynthesis of marine prostaglandins via the allene oxide synthase pathway. Brash_AR et al.. | |
| 8(R)-HETE induces maturation of starfish oocytes at a concentration of 0.071 μ M Meijer_L et al.. This activity if neglible in the 8(S)-enantiomer Meijer_L et al.. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | λ max: 237nm ε : 27,000 |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | |||||||||||||||
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