LBF20406LT10: Difference between revisions

Latest revision as of 16:52, 21 October 2010

Upper classes: LB LBF

14,15-dehydro Leukotriene B₄

Structural Information
	(5S,12R) -Dihydroxy- (cis-6,trans-8,trans-10) -eicosatriene-14-ynoic acid
	14,15-dehydro Leukotriene B₄ (5S,12R) -Dihydroxy- (6Z,8E,10E) -eicosatriene-14-ynoic acid

Formula	C20H30O4
Exact Mass	334.21440944799997
Average Mass	334.4498
SMILES	`C(CC#CC[C@H](C=CC=CC=C[C@H](CCCC(O)=O)O)O)CCC`
Physicochemical Information









	14,15-dehydro LTB4 is reported as a selective ligand for the BLT1 and act as a selective antagonist of LTB4 in vivo. Wang_S et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20406LT10	See above.	Wang_S et al. 2000

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
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 |LipidBank=XPR3119
 |LipidMaps=LMFA03020017
-|SysName=5S,12R-dihydroxy-6Z,8E,10E-eicosatriene-14-ynoic acid
+|SysName=(5S,12R) -Dihydroxy- (cis-6,trans-8,trans-10) -eicosatriene-14-ynoic acid
-|Common Name=&&14,15-dehydro Leukotriene B4&&5S,12R-dihydroxy-6Z,8E,10E-eicosatriene-14-ynoic acid&&
+|Common Name=&&14,15-dehydro Leukotriene B_4&&(5S,12R) -Dihydroxy- (6Z,8E,10E) -eicosatriene-14-ynoic acid&&
+|Source=
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=14,15-dehydro LTB4 is reported as a selective ligand for the BLT1 and act as a selective antagonist of LTB4 in vivo.[[Reference:Wang_S:Gustafson_E:Pang_L:Qiao_X:Behan_J:Maguire_M:Bayne_M:Laz_T:,J. Biol. Chem.,2000,275,40686|{{RelationTable/GetFirstAuthor|Reference:Wang_S:Gustafson_E:Pang_L:Qiao_X:Behan_J:Maguire_M:Bayne_M:Laz_T:,J. Biol. Chem.,2000,275,40686}}]]
 }}
+{{Lipid/Footer}}