LBF20407HO05: Difference between revisions

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{{Lipid/Header}}
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|LipidBank=DFA8139
|LipidBank=DFA8139
|LipidMaps=LMFA03060030
|LipidMaps=LMFA03060030
|SysName=15R-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
|SysName=15R-Hydroxy- (cis-5,cis-8,trans-10,cis-14) -eicosatetraenoic acid
|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 236nm <FONT FACE="Symbol">e</FONT>: 27,000
|Common Name=&&15R-Hydroxy- (5Z,8Z,10E,14Z) -eicosatetraenoic acid&&
|UV Spectra= lambda max: 236nm epsilon : 27,000
|Source=
|Chemical Synthesis=
|Metabolism=(±)15-HETE, an autoxidation product of arachidonic acid, is comprised of an equal mixture of 15(R)- and 15(S)-HETE. Aspirin-inactivated human recombinant and ovine COX-2 metabolizes arachidonic acid to 15(R)-HETE [[Reference:Lecomte_M:Laneuville_O:Ji_C:DeWitt_DL:Smith_WL:,J. Biol. Chem.,1994,269,13207|{{RelationTable/GetFirstAuthor|Reference:Lecomte_M:Laneuville_O:Ji_C:DeWitt_DL:Smith_WL:,J. Biol. Chem.,1994,269,13207}}]][[Reference:Capdevila_JH:Morrow_JD:Belosludtsev_YY:Beauchamp_DR:DuBois_RN:Falck_JR:,Biochemistry,1995,34,3325|{{RelationTable/GetFirstAuthor|Reference:Capdevila_JH:Morrow_JD:Belosludtsev_YY:Beauchamp_DR:DuBois_RN:Falck_JR:,Biochemistry,1995,34,3325}}]].
|Symbol=15(R)-HETE
}}
}}
{{Lipid/Footer}}

Latest revision as of 07:34, 21 October 2010

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Upper classes: LB LBF



15R-Hydroxy- (5Z,8Z,10E,14Z) -eicosatetraenoic acid
LBF20407HO05.png
Structural Information
15R-Hydroxy- (cis-5,cis-8,trans-10,cis-14) -eicosatetraenoic acid
  • 15R-Hydroxy- (5Z,8Z,10E,14Z) -eicosatetraenoic acid
15(R)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC[C@H](C=CC=CCC=CCC=CCCCC(O)=O)O)CC
Physicochemical Information
(±)15-HETE, an autoxidation product of arachidonic acid, is comprised of an equal mixture of 15(R)- and 15(S)-HETE. Aspirin-inactivated human recombinant and ovine COX-2 metabolizes arachidonic acid to 15(R)-HETE Lecomte_M et al. Capdevila_JH et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20407HO05 See above. Capdevila_JH et al. 1995
n.a. LBF20407HO05 See above. Lecomte_M et al. 1994