LBF20503HO01: Difference between revisions
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|LipidBank=DFA8119 | |LipidBank=DFA8119 | ||
|LipidMaps=LMFA03070002 | |LipidMaps=LMFA03070002 | ||
|SysName= | |SysName=8R-Hydroxy- (cis-5,trans-9,cis-11,cis-14,cis-17) -eicosapentaenoic acid | ||
|Common Name=&& | |Common Name=&&8R-Hydroxy- (5Z,9E,11Z,14Z,17Z) -eicosapentaenoic acid&& | ||
|UV Spectra= lambda max: 236nm epsilon : 23,000 | |UV Spectra= lambda max: 236nm epsilon : 23,000 | ||
|Source=(±)8-HEPE is the major eicosanoid extract from the barnacle, E. modestus. <!--8146-->. | |Source=(±)8-HEPE is the major eicosanoid extract from the barnacle, E. modestus. <!--8146-->. | ||
|Chemical Synthesis= | |Chemical Synthesis= | ||
|Metabolism= | |Metabolism= | ||
|Symbol=( | |Symbol=(+-)8-HEPE | ||
|Biological Activity=(±)8-HEPE causes barnacle eggs to hatch with an IC_{50} = 2.4 x 10^{-6} M [[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]]. Reports conflict as to whether the barnacle hatching activity is a result of the 8(R)-or the 8(S)-enantiomer <!--8146-->[[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]][[Reference:Hill_EM:Holland_DL:,Proc. Biol. Sci.,1992,247,41|{{RelationTable/GetFirstAuthor|Reference:Hill_EM:Holland_DL:,Proc. Biol. Sci.,1992,247,41}}]]. Apparently, only the 8(R)-HEPE induces oocyte maturation in the starfish [[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]]. | |Biological Activity=(±)8-HEPE causes barnacle eggs to hatch with an IC_{50} = 2.4 x 10^{-6} M [[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]]. Reports conflict as to whether the barnacle hatching activity is a result of the 8(R)-or the 8(S)-enantiomer <!--8146-->[[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]][[Reference:Hill_EM:Holland_DL:,Proc. Biol. Sci.,1992,247,41|{{RelationTable/GetFirstAuthor|Reference:Hill_EM:Holland_DL:,Proc. Biol. Sci.,1992,247,41}}]]. Apparently, only the 8(R)-HEPE induces oocyte maturation in the starfish [[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]]. | ||
}} | }} | ||
{{Lipid/Footer}} | {{Lipid/Footer}} | ||
Latest revision as of 02:47, 27 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | DFA8119 |
| LipidMaps | LMFA03070002 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20503HO01 |
| 8R-Hydroxy- (5Z,9E,11Z,14Z,17Z) -eicosapentaenoic acid | |
|---|---|
| |
| Structural Information | |
| 8R-Hydroxy- (cis-5,trans-9,cis-11,cis-14,cis-17) -eicosapentaenoic acid | |
| |
| (+-)8-HEPE | |
| Formula | C20H30O3 |
| Exact Mass | 318.21949482599996 |
| Average Mass | 318.4504 |
| SMILES | C(CC=CCC=CC=C[C@@H](CC=CCCCC(O)=O)O)=CCC |
| Physicochemical Information | |
| (±)8-HEPE is the major eicosanoid extract from the barnacle, E. modestus. . | |
| (±)8-HEPE causes barnacle eggs to hatch with an IC_{50} = 2.4 x 10^{-6} M Shing_TKM et al.. Reports conflict as to whether the barnacle hatching activity is a result of the 8(R)-or the 8(S)-enantiomer Shing_TKM et al. Hill_EM et al.. Apparently, only the 8(R)-HEPE induces oocyte maturation in the starfish Shing_TKM et al.. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | λ max: 236nm ε : 23,000 |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | |||||||||||||||
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