LBF20406OX01

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	DFA8156
LipidMaps	LMFA03060011
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20406OX01

5-Oxo- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
Structural Information
Systematic Name	5-Oxo- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
Common Name	5-Oxo- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
Symbol	5-OxoETE/5-KETE
Formula	C20H30O3
Exact Mass	318.21949482599996
Average Mass	318.4504
SMILES	C(CC=CCC=CCC=CC=CC(CCCC(O)=O)=O)CCC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility
Source	5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils Powell_WS et al..
Chemical Synthesis
Metabolism
Biological Activity	It stimulates cytosolic calcium levels in neutrophils with an EC of 2 nM Powell_WS et al.. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils OFlaherty_JT et al. OFlaherty_JT et al..
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra	λ max: 279nm ε : 22,100
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20406OX01 See above. OFlaherty_JT et al. 1996 n.a. LBF20406OX01 See above. OFlaherty_JT et al. 1996 n.a. LBF20406OX01 See above. Powell_WS et al. 1992 n.a. LBF20406OX01 See above. Powell_WS et al. 1994

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  UT000186
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  UT000188
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  UT000189