LBF20107PG21: Difference between revisions

Latest revision as of 17:15, 21 October 2010

Upper classes: LB LBF

6β-Prostaglandin I₁

Structural Information
	(6S,9α) -Epoxy- (11α,15S) -dihydroxy-prost-trans-13-en-1-oic acid
	6β-Prostaglandin I₁ (6S,9α) -Epoxy- (11α,15S) -dihydroxy-prost-13(E)-en-1-oic acid

Formula	C20H34O5
Exact Mass	354.240624198
Average Mass	354.48096000000004
SMILES	`C(CC[C@H](O)C=C[C@H]([C@H]12)[C@H](O)C[C@H](O[C@H](C2)CCCCC(O)=O)1)CC`
Physicochemical Information









	6 beta -PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 mu M compared with 18 nM for PGI2. Whittle_BJ et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20107PG21	See above.	Whittle_BJ et al. 1980

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
@@ Line 4: / Line 6: @@
 |LipidBank=XPR1800
 |LipidMaps=LMFA03010129
-|SysName=6S,9a-epoxy-11a,15S-dihydroxy-prost-13E-en-1-oic acid
+|SysName=(6S,9alpha) -Epoxy- (11alpha,15S) -dihydroxy-prost-trans-13-en-1-oic acid
-|Common Name=&&6b-Prostaglandin I_1&&
+|Common Name=&&6beta-Prostaglandin I_1&&(6S,9alpha) -Epoxy- (11alpha,15S) -dihydroxy-prost-13(E)-en-1-oic acid&&
+|Source=
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=6 beta -PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2  mu M compared with 18 nM for PGI2.[[Reference:Whittle_BJ:Moncada_S:Whiting_F:Vane_JR:,Prostaglandins,1980,19,605|{{RelationTable/GetFirstAuthor|Reference:Whittle_BJ:Moncada_S:Whiting_F:Vane_JR:,Prostaglandins,1980,19,605}}]]
 }}
+{{Lipid/Footer}}