LBF20207PG41: Difference between revisions

Latest revision as of 03:13, 2 November 2010

Upper classes: LB LBF

15(R) - Prostaglandin D₂

Structural Information
	(9S,15R) -Dihydroxy-11-oxo- (cis-5,trans-13) -prostadienoic acid
	15(R) - Prostaglandin D₂ (9S,15R) -Dihydroxy-11-oxo- (5Z,13E) -prostadienoic acid (9α,15R) -Dihydroxy-11-oxo-prosta- (5Z,13E) -dien-1-oic acid

Formula	C20H32O5
Exact Mass	352.224974134
Average Mass	352.46508
SMILES	`C(CC[C@@H](O)C=C[C@H]([C@H]1CC=CCCCC(O)=O)C(C[C@@H]1O)=O)CC`
Physicochemical Information









	15(R)-PGD2 is reported to have potent agonistic effect to the DP2 receptor 5 time higher than PGD2. Giles_H et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20207PG41	See above.	Giles_H et al. 1989

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
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 |LipidBank=XPR1772
 |LipidMaps=LMFA03010102
-|SysName=9a,15R-dihydroxy-11-oxo-prosta-5E,13E-dien-1-oic acid
+|SysName=(9S,15R) -Dihydroxy-11-oxo- (cis-5,trans-13) -prostadienoic acid
-|Common Name=&&15 (R) -Prostaglandin D_2&&9a,15R-dihydroxy-11-oxo-prosta-5E,13E-dien-1-oic acid&&
+|Common Name=&&15(R) - Prostaglandin D_2&&(9S,15R) -Dihydroxy-11-oxo- (5Z,13E) -prostadienoic acid&&(9alpha,15R) -Dihydroxy-11-oxo-prosta- (5Z,13E) -dien-1-oic acid&&
+|Source=
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=15(R)-PGD2 is reported to have potent agonistic effect to the DP2 receptor 5 time higher than PGD2.[[Reference:Giles_H:Leff_P:Bolofo_ML:Kelly_MG:Robertson_AD:,Br. J. Pharmacol.,1989,96,291|{{RelationTable/GetFirstAuthor|Reference:Giles_H:Leff_P:Bolofo_ML:Kelly_MG:Robertson_AD:,Br. J. Pharmacol.,1989,96,291}}]]
 }}
+{{Lipid/Footer}}