LBF20306HO02: Difference between revisions
No edit summary |
No edit summary |
||
(15 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
{{Lipid/Header}} | |||
{{Hierarchy|{{PAGENAME}}}} | {{Hierarchy|{{PAGENAME}}}} | ||
Line 4: | Line 6: | ||
|LipidBank=DFA8107 | |LipidBank=DFA8107 | ||
|LipidMaps=LMFA03050006 | |LipidMaps=LMFA03050006 | ||
|SysName= | |SysName=dl-8,9-Dihydroxy- (cis-5,cis-11,cis-14) -eicosatrienoic acid | ||
|Common Name=&&(+-) 8,9- | |Common Name=&&(+-) -8,9-Dihydroxy- (5Z,11Z,14Z) -eicosatrienoic acid&& | ||
|Source= | |||
|Chemical Synthesis= | |||
|Metabolism= | |||
|Symbol=(+-)8,9-DiHETrE | |||
|Biological Activity=Epoxide hydrolases convert the EpETrEs into vicinal diols[[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]], with the concurrent loss of much of their biological activity. The 8(S),9(R)-EpETrE isomer is metabolized by platelet cyclooxygenase to form 8(S),9(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor[[Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138|{{RelationTable/GetFirstAuthor|Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138}}]]. | |||
}} | }} | ||
{{Lipid/Footer}} |
Latest revision as of 07:19, 21 October 2010
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
---|---|
LipidBank | DFA8107 |
LipidMaps | LMFA03050006 |
CAS | |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20306HO02 |
(+-) -8,9-Dihydroxy- (5Z,11Z,14Z) -eicosatrienoic acid | |
---|---|
Structural Information | |
dl-8,9-Dihydroxy- (cis-5,cis-11,cis-14) -eicosatrienoic acid | |
| |
(+-)8,9-DiHETrE | |
Formula | C20H34O4 |
Exact Mass | 338.24570957599997 |
Average Mass | 338.48156 |
SMILES | C(CC=CCC=CCC(O)C(O)CC=CCCCC(O)=O)CCC |
Physicochemical Information | |
Epoxide hydrolases convert the EpETrEs into vicinal diols Oliw_EH et al., with the concurrent loss of much of their biological activity. The 8(S),9(R)-EpETrE isomer is metabolized by platelet cyclooxygenase to form 8(S),9(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor Zhang_JY et al.. | |
Spectral Information | |
Mass Spectra | |
UV Spectra | |
IR Spectra | |
NMR Spectra | |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|