LBF20406AM29: Difference between revisions
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{{Metabolite | {{Metabolite | ||
|LipidBank=XPR7046 | |LipidBank=XPR7046 | ||
|LipidMaps= | |LipidMaps=LMFA08040017 | ||
|SysName= | |SysName=N-2,2-Dimethy- (cis-5,cis-8,cis-11,cis-14) -eicosatetraenoylethanolamine | ||
|Common Name=&&alpha,alpha- | |Common Name=&&alpha,alpha-Dimethylanandamide&&N-2,2-Dimethy- (5Z,8Z,11Z,14Z) -eicosatetraenoylethanolamine&& | ||
|Melting Point=colorless oil[[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | |Melting Point=colorless oil[[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | ||
|NMR Spectra= | |NMR Spectra=^1 H NMR (CDCl3) delta 6.10 (br s, lH), 5.30-5.42 (m, 8H), 3.75 (t, J=5.l Hz, 2H), 3.42 (q, J=4.9Hz, 2H), 2.78-2.86 (m, 6H), 2.00-2.10 (m, 4H), 1.50-1.62 (m, 4H), 1.24-1.40 (m, 4H), 1.22 (s, 6H), 0.90 (t, J=6.9 Hz, 3H). [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | ||
|Source= | |Source= | ||
|Chemical Synthesis=This compound was synthesized from arachidonic acid and ethanolamine. Yield 47 %.[[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | |Chemical Synthesis=This compound was synthesized from arachidonic acid and ethanolamine. Yield 47 %.[[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | ||
|Metabolism= | |Metabolism= | ||
|Biological Activity=Binding to the brain cannabinoid receptor (CBl), Ki(nM)= 25.5±2.8 [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]] | |||
}} | }} | ||
{{Lipid/Footer}} | {{Lipid/Footer}} | ||
Latest revision as of 04:47, 21 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | XPR7046 |
| LipidMaps | LMFA08040017 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406AM29 |
| α,α-Dimethylanandamide | |
|---|---|
| |
| Structural Information | |
| N-2,2-Dimethy- (cis-5,cis-8,cis-11,cis-14) -eicosatetraenoylethanolamine | |
| |
| Formula | C24H41NO2 |
| Exact Mass | 375.313729561 |
| Average Mass | 375.58788 |
| SMILES | C(CC=CCCC(C(NCCO)=O)(C)C)=CCC=CCC=CCCCCC |
| Physicochemical Information | |
| colorless oil Sheskin_T et al. | |
| This compound was synthesized from arachidonic acid and ethanolamine. Yield 47 %. Sheskin_T et al. | |
| Binding to the brain cannabinoid receptor (CBl), Ki(nM)= 25.5±2.8 Sheskin_T et al. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | |
| IR Spectra | |
| NMR Spectra | 1H NMR (CDCl3) δ 6.10 (br s, lH), 5.30-5.42 (m, 8H), 3.75 (t, J=5.l Hz, 2H), 3.42 (q, J=4.9Hz, 2H), 2.78-2.86 (m, 6H), 2.00-2.10 (m, 4H), 1.50-1.62 (m, 4H), 1.24-1.40 (m, 4H), 1.22 (s, 6H), 0.90 (t, J=6.9 Hz, 3H). SheskinTet al. |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | ||||||||||
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