LBF20406LT09: Difference between revisions

Latest revision as of 07:52, 21 October 2010

Upper classes: LB LBF

20-carboxy Leukotriene B₄

Structural Information
	(5S,12R) -Dihydroxy- (cis-6,trans-8,trans-10,cis-14) -eicosatetraenoic acid
	20-carboxy Leukotriene B₄ (5S,12R) -Dihydroxy- (6Z,8E,10E,14Z) -eicosatetraenoic acid

Formula	C20H30O6
Exact Mass	366.204238692
Average Mass	366.4486
SMILES	`C(CCCC(O)=O)C=CC[C@H](C=CC=CC=C[C@H](CCCC(O)=O)O)O`
Physicochemical Information






	20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils


	The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degradation. Feinmark_SJ et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20406LT09	See above.	Feinmark_SJ et al. 1981

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
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 |LipidBank=XPR3118
 |LipidMaps=LMFA03020016
-|SysName=5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid
+|SysName=(5S,12R) -Dihydroxy- (cis-6,trans-8,trans-10,cis-14) -eicosatetraenoic acid
-|Common Name=&&20-carboxy Leukotriene B4&&5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid&&
+|Common Name=&&20-carboxy Leukotriene B_4&&(5S,12R) -Dihydroxy- (6Z,8E,10E,14Z) -eicosatetraenoic acid
+|Source=20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degradation.[[Reference:Feinmark_SJ:Lindgren_JA:Claesson_HE:Malmsten_C:Samuelsson_B:,FEBS Lett.,1981,136,141|{{RelationTable/GetFirstAuthor|Reference:Feinmark_SJ:Lindgren_JA:Claesson_HE:Malmsten_C:Samuelsson_B:,FEBS Lett.,1981,136,141}}]]
 }}
+{{Lipid/Footer}}