LBF20407HO02: Difference between revisions

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Latest revision as of 16:34, 21 October 2010

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(脂肪酸)

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Upper classes: LB LBF

(5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid

Structural Information
	(5S,15S) -Dihydroxy- (trans-6,cis-8,cis-10,trans-13) -eicosatetraenoic acid
	(5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid
	5(S),15(S)-DiHETE
Formula	C20H32O4
Exact Mass	336.23005951199997
Average Mass	336.46567999999996
SMILES	`C(CCC(C=CCC=CC=CC=CC(CCCC(O)=O)O)O)CC`
Physicochemical Information






	5(S),15(S)-DiHETE is synthesized by 15-lipoxygenase from 5(S)-HETE Green_FA .


	5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 OFlaherty_JT et al.. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED_{50} of 0.3 μ M Morita_E et al..


Spectral Information
Mass Spectra
UV Spectra	λ max: 243nm ε : 33,500
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference
n.a.	LBF20407HO02	See above.	Green_FA 1990
n.a.	LBF20407HO02	See above.	Morita_E et al. 1990
n.a.	LBF20407HO02	See above.	OFlaherty_JT et al. 1985

@@ Line 1: / Line 1: @@
+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
@@ Line 4: / Line 6: @@
 |LipidBank=DFA8104
 |LipidMaps=-
-|SysName=5S,15S-dihydroxy-6E,8Z,10Z,13E-eicosatetraenoic acid
+|SysName=(5S,15S) -Dihydroxy- (trans-6,cis-8,cis-10,trans-13) -eicosatetraenoic acid
-|Common Name=&&5S,15S-dihydroxy-6E,8Z,10Z,13E-eicosatetraenoic acid&&
+|Common Name=&&(5S,15S) -Dihydroxy- (6E,8Z,10Z,13E) -eicosatetraenoic acid&&
-|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 243nm <FONT FACE="Symbol">e</FONT>: 33,500
+|UV Spectra= lambda max: 243nm  epsilon : 33,500
+|Source=5(S),15(S)-DiHETE is synthesized by 15-lipoxygenase from 5(S)-HETE [[Reference:Green_FA:,Lipids,1990,25,618|{{RelationTable/GetFirstAuthor|Reference:Green_FA:,Lipids,1990,25,618}}]].
+|Chemical Synthesis=
+|Metabolism=
+|Symbol=5(S),15(S)-DiHETE
+|Biological Activity=5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 [[Reference:OFlaherty_JT:Thomas_MJ:,Prostaglandins Leukot. Med.,1985,17,199|{{RelationTable/GetFirstAuthor|Reference:OFlaherty_JT:Thomas_MJ:,Prostaglandins Leukot. Med.,1985,17,199}}]]. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED_{50} of 0.3  &mu; M[[Reference:Morita_E:Schroder_JM:Christophers_E:,J. Immunol.,1990,144,1893|{{RelationTable/GetFirstAuthor|Reference:Morita_E:Schroder_JM:Christophers_E:,J. Immunol.,1990,144,1893}}]].
 }}
+{{Lipid/Footer}}

IDs and Links
LipidBank	DFA8104
LipidMaps	-
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}

mol	LBF20407HO02

LBF20407HO02: Difference between revisions

Latest revision as of 16:34, 21 October 2010

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