LBF20503HO06: Difference between revisions

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(脂肪酸)

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Upper classes: LB LBF

12R-Hydroxy- (5Z,8Z,10E,14Z,17Z) -eicosapentaenoic acid

Structural Information
	12R-Hydroxy- (cis-5,cis-8,trans-10,cis-14,cis-17) -eicosapentaenoic acid
	12R-Hydroxy- (5Z,8Z,10E,14Z,17Z) -eicosapentaenoic acid
	12(R)-HEPE
Formula	C20H30O3
Exact Mass	318.21949482599996
Average Mass	318.4504
SMILES	`C(CC=CC=C(CCC=CCC=CCCCC(O)=O)O)=CCC`
Physicochemical Information






	12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin S. purpuratus Hawkins_DJ et al..


	The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE Masferrer_JL et al. Conners_MS et al..


Spectral Information
Mass Spectra
UV Spectra	λ max: 237nm ε : 23,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference
n.a.	LBF20503HO06	See above.	Conners_MS et al. 1995
n.a.	LBF20503HO06	See above.	Hawkins_DJ et al. 1987
n.a.	LBF20503HO06	See above.	Masferrer_JL et al. 1990

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
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 |LipidBank=DFA8124
 |LipidMaps=LMFA03070007
-|SysName=12R-hydroxy-5Z,8Z,12E,14Z,17Z-Eicosapentaenoic acid
+|SysName=12R-Hydroxy- (cis-5,cis-8,trans-10,cis-14,cis-17) -eicosapentaenoic acid
-|Common Name=&&12R-hydroxy-5Z,8Z,12E,14Z,17Z-Eicosapentaenoic acid&&
+|Common Name=&&12R-Hydroxy- (5Z,8Z,10E,14Z,17Z) -eicosapentaenoic acid&&
-|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 237nm <FONT FACE="Symbol">e</FONT>: 23,000
+|UV Spectra= lambda max: 237nm  epsilon : 23,000
+|Source=12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin S. purpuratus [[Reference:Hawkins_DJ:Brash_AR:,J. Biol. Chem.,1987,262,7629|{{RelationTable/GetFirstAuthor|Reference:Hawkins_DJ:Brash_AR:,J. Biol. Chem.,1987,262,7629}}]].
+|Chemical Synthesis=
+|Metabolism=
+|Symbol=12(R)-HEPE
+|Biological Activity=The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE [[Reference:Masferrer_JL:Dunn_MW:Schwartzman_ML:,Invest. Ophthalmol. Vis. Sci.,1990,31,535|{{RelationTable/GetFirstAuthor|Reference:Masferrer_JL:Dunn_MW:Schwartzman_ML:,Invest. Ophthalmol. Vis. Sci.,1990,31,535}}]][[Reference:Conners_MS:Schwartzman_ML:Quan_X:Heilman_E:Chauhan_K:Falck_JR:Godfrey_HP:,J. Invest. Dermatol.,1995,104,47|{{RelationTable/GetFirstAuthor|Reference:Conners_MS:Schwartzman_ML:Quan_X:Heilman_E:Chauhan_K:Falck_JR:Godfrey_HP:,J. Invest. Dermatol.,1995,104,47}}]].
 }}
+{{Lipid/Footer}}

IDs and Links
LipidBank	DFA8124
LipidMaps	LMFA03070007
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}

mol	LBF20503HO06

LBF20503HO06: Difference between revisions

Latest revision as of 16:37, 21 October 2010

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