LBF20207PG52: Difference between revisions

Revision as of 23:00, 19 February 2010

Upper classes: LB LBF

15 (R) -Prostaglandin F_2α

Structural Information
	9α,11α,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid
	15 (R) -Prostaglandin F_2α 9α,11α,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid

Formula	C20H34O5
Exact Mass	354.240624198
Average Mass	354.48096000000004
SMILES	`C(CC[C@H](O)C=C[C@H]([C@H]1CC=CCCCC(O)=O)[C@@H](C[C@@H]1O)O)CC`
Physicochemical Information






	15(R)-PGF2 alpha is the C-15 epimer of the naturally occurring PGF2 alpha .


	15(R)-PGF2 alpha has only quarter of the ability of PGF2 alpha in hamster antifertility studies Miller_WL et al. due to reduced affinity for FP receptors.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20207PG52	See above.	Miller_WL et al. 1976

@@ Line 8: / Line 8: @@
 |SysName=9alpha,11alpha,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid
 |Common Name=&&15 (R) -Prostaglandin F_2alpha&&9alpha,11alpha,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid&&
-|Source=15(R)-PGF2alpha is the C-15 epimer of the naturally occurring PGF2alpha.
+|Source=15(R)-PGF2 alpha  is the C-15 epimer of the naturally occurring PGF2 alpha .
 |Chemical Synthesis=
 |Metabolism=
-|Biological Activity=15(R)-PGF2alpha has only quarter of the ability of PGF2alpha in hamster antifertility studies[[Reference:Miller_WL:Sutton_MJ:,Prostaglandins,1976,11,77|{{RelationTable/GetFirstAuthor|Reference:Miller_WL:Sutton_MJ:,Prostaglandins,1976,11,77}}]] due to reduced affinity for FP receptors.
+|Biological Activity=15(R)-PGF2 alpha  has only quarter of the ability of PGF2 alpha  in hamster antifertility studies[[Reference:Miller_WL:Sutton_MJ:,Prostaglandins,1976,11,77|{{RelationTable/GetFirstAuthor|Reference:Miller_WL:Sutton_MJ:,Prostaglandins,1976,11,77}}]] due to reduced affinity for FP receptors.
 }}
 {{Lipid/Footer}}