LBF20308PG01: Difference between revisions

Revision as of 21:00, 14 April 2010

Upper classes: LB LBF

Δ¹²-Prostaglandin J₂

Structural Information
	11-oxo-15S-hydroxy-prosta-5Z,9,12E-trien-1-oic acid
	Δ¹²-Prostaglandin J₂

Formula	C20H30O4
Exact Mass	334.21440944799997
Average Mass	334.4498
SMILES	`C(CC[C@@H](O)CC=C(C(=O)1)[C@@H](CC=CCCCC(O)=O)C=C1)CC`
Physicochemical Information






	Delta ^{12}-PGJ2 is a decomposition product of PGD2 in the presence of albumin. Fitzpatrick_FA et al.


	Delta ^{12}-PGJ2 has antitumor and antibiral activity, inhibiting growth of cultured L1210 cells with an IC50 of 0.7 mu g/ml. Kato_T et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20308PG01	See above.	Fitzpatrick_FA et al. 1983
n.a.	LBF20308PG01	See above.	Kato_T et al. 1986

@@ Line 7: / Line 7: @@
 |LipidMaps=LMFA03010020
 |SysName=11-oxo-15S-hydroxy-prosta-5Z,9,12E-trien-1-oic acid
-|Common Name=&&Delta^{12}-Prostaglandin J_2&&11-oxo-15S-hydroxy-prosta-5Z,9,12E-trien-1-oic acid&&
+|Common Name=&&Delta^{12}-Prostaglandin J_2&&
 |Source= Delta ^{12}-PGJ2 is a decomposition product of PGD2 in the presence of albumin.[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]
 |Chemical Synthesis=